Accepted Manuscript Compared with cystectomy, is ovarian vaporization of endometriotic cysts truly more effective in maintaining ovarian reserve? Natsuho Saito, M.D Kiyoji Okuda, M.D Hiroko Yuguchi, M.D Yoshiki Yamashita, M.D Yoshito Terai, M.D Masahide Ohmichi, M.D PII:
S1553-4650(14)00203-9
DOI:
10.1016/j.jmig.2014.03.008
Reference:
JMIG 2274
To appear in:
The Journal of Minimally Invasive Gynecology
Received Date: 24 December 2013 Revised Date:
10 March 2014
Accepted Date: 11 March 2014
Please cite this article as: Saito N, Okuda K, Yuguchi H, Yamashita Y, Terai Y, Ohmichi M, Compared with cystectomy, is ovarian vaporization of endometriotic cysts truly more effective in maintaining ovarian reserve?, The Journal of Minimally Invasive Gynecology (2014), doi: 10.1016/j.jmig.2014.03.008. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT 1
Compared with cystectomy, is ovarian vaporization of endometriotic cysts
2
truly more effective in maintaining ovarian reserve?
RI PT
3
4
Natsuho Saito, M.D., Kiyoji Okuda, M.D., Hiroko Yuguchi, M.D., Yoshiki
6
Yamashita, M.D., Yoshito Terai, M.D., Masahide Ohmichi, M.D.
7
Department obstetrics and gynecology, Hokusetsu General Hospital (Drs. Saito,
8
Okuda and Yuguchi). Department obstetrics and gynecology, Osaka Medical
9
College (Drs. Yamashita, Terai and Ohmichi)
M AN U
SC
5
TE D
10
Corresponding author contact information: Yoshiki Yamashita, M.D.,
12
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7
13
Daigakumachi, Takatsuki, Osaka 569-8686, Japan
14
E-mail: [email protected]
15
Key words : endometriotic cyst, laparoscopic surgery, ovarian reserve, FSH,
16
AMH
AC C
EP
11
17
1
ACCEPTED MANUSCRIPT
Abstract:
19
Objective: It remains controversial as to which conservative surgery for
20
endometriotic cysts is more beneficial for preserving ovarian reserve. We
21
have initiated a study with the objective of evaluating how endometriotic
22
cystectomy and vaporization affect ovarian reserve following conservative
23
surgery.
24
Design: Prospective study.
25
Design classification: II-1
26
Setting: Hokusetsu General Hospital
27
Patients: Ninety-nine women who underwent conservative surgery for
28
endometriotic cysts from June 2011 to July 2013 in Hokusetsu General
29
Hospital.
30
Interventions: Vaporization with bipolar current was adopted for the
31
nulligravid women and a cystectomy was carried out on those who already had
32
a child. In endometriotic cyst, 28 women undertook a bilateral cystectomy
33
(BC), 15 undertook bilateral vaporization (BV), 40 undertook a unilateral
34
cystectomy (UC), and 16 undertook unilateral vaporization (UV). In all cases,
35
preoperatively and postoperatively, serum AMH and FSH levels at the early
36
proliferative phase were assayed and the change in their levels was evaluated
AC C
EP
TE D
M AN U
SC
RI PT
18
2
ACCEPTED MANUSCRIPT
according to operation.
38
Results: In the BC group, the postoperative FSH level (19.3±21.8 IU/ml) was
39
statistically higher than the preoperative level (9.0±6.2 IU/ml) (p
S1553-4650(14)00203-9
DOI:
10.1016/j.jmig.2014.03.008
Reference:
JMIG 2274
To appear in:
The Journal of Minimally Invasive Gynecology
Received Date: 24 December 2013 Revised Date:
10 March 2014
Accepted Date: 11 March 2014
Please cite this article as: Saito N, Okuda K, Yuguchi H, Yamashita Y, Terai Y, Ohmichi M, Compared with cystectomy, is ovarian vaporization of endometriotic cysts truly more effective in maintaining ovarian reserve?, The Journal of Minimally Invasive Gynecology (2014), doi: 10.1016/j.jmig.2014.03.008. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT 1
Compared with cystectomy, is ovarian vaporization of endometriotic cysts
2
truly more effective in maintaining ovarian reserve?
RI PT
3
4
Natsuho Saito, M.D., Kiyoji Okuda, M.D., Hiroko Yuguchi, M.D., Yoshiki
6
Yamashita, M.D., Yoshito Terai, M.D., Masahide Ohmichi, M.D.
7
Department obstetrics and gynecology, Hokusetsu General Hospital (Drs. Saito,
8
Okuda and Yuguchi). Department obstetrics and gynecology, Osaka Medical
9
College (Drs. Yamashita, Terai and Ohmichi)
M AN U
SC
5
TE D
10
Corresponding author contact information: Yoshiki Yamashita, M.D.,
12
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7
13
Daigakumachi, Takatsuki, Osaka 569-8686, Japan
14
E-mail: [email protected]
15
Key words : endometriotic cyst, laparoscopic surgery, ovarian reserve, FSH,
16
AMH
AC C
EP
11
17
1
ACCEPTED MANUSCRIPT
Abstract:
19
Objective: It remains controversial as to which conservative surgery for
20
endometriotic cysts is more beneficial for preserving ovarian reserve. We
21
have initiated a study with the objective of evaluating how endometriotic
22
cystectomy and vaporization affect ovarian reserve following conservative
23
surgery.
24
Design: Prospective study.
25
Design classification: II-1
26
Setting: Hokusetsu General Hospital
27
Patients: Ninety-nine women who underwent conservative surgery for
28
endometriotic cysts from June 2011 to July 2013 in Hokusetsu General
29
Hospital.
30
Interventions: Vaporization with bipolar current was adopted for the
31
nulligravid women and a cystectomy was carried out on those who already had
32
a child. In endometriotic cyst, 28 women undertook a bilateral cystectomy
33
(BC), 15 undertook bilateral vaporization (BV), 40 undertook a unilateral
34
cystectomy (UC), and 16 undertook unilateral vaporization (UV). In all cases,
35
preoperatively and postoperatively, serum AMH and FSH levels at the early
36
proliferative phase were assayed and the change in their levels was evaluated
AC C
EP
TE D
M AN U
SC
RI PT
18
2
ACCEPTED MANUSCRIPT
according to operation.
38
Results: In the BC group, the postoperative FSH level (19.3±21.8 IU/ml) was
39
statistically higher than the preoperative level (9.0±6.2 IU/ml) (p
