EVIDENCE-BASED CHILD HEALTH: A COCHRANE REVIEW JOURNAL Evid.-Based Child Health 9: 672–674 (2014) Published online in Wiley Online Library (http://www.evidence-basedchildhealth.com). DOI: 10.1002/ebch.1977
Commentary Cochrane in context: Probiotics for prevention of necrotizing enterocolitis in preterm infants Cochrane Review: Probiotics for prevention of necrotizing enterocolitis in preterm infants AlFaleh K, Anabrees J. Probiotics for prevention of necrotizing enterocolitis in preterm infants. Cochrane Database of Systematic Reviews 2014, Issue 4. Art. No.: CD005496. DOI: 10.1002/14651858.CD005496.pub4. This companion piece to the review, “Probiotics for prevention of necrotizing enterocolitis in preterm infants,” contains the following pieces: • The abstract of the review • A commentary from Joan Robinson, editor-in-chief for Evidence-Based Child Health, discussing the importance of this review • A review of clinical practice guidelines • Some other recently published references on this topic
Evidence-Based Child Health: a Cochrane Review Journal is now indexed by MEDLINE (http://www.ncbi. nlm.nih.gov/pubmed) and Scopus (http://www.scopus.com)
Abstract Background Necrotizing enterocolitis (NEC) and nosocomial sepsis are associated with increased morbidity and mortality in preterm infants. Through prevention of bacterial migration across the mucosa, competitive exclusion of pathogenic bacteria and by enhancing the immune responses of the host, prophylactic enteral probiotics (live microbial supplements) may play a role in reducing NEC and the associated morbidity. Objectives To compare the efficacy and safety of prophylactic enteral probiotics administration versus placebo or no treatment in the prevention of severe NEC or sepsis, or both, in preterm infants. Search methods For this update, searches were made of MEDLINE (1966 to October 2013), EMBASE (1980 to October 2013), the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library (2013, Issue 10), and abstracts of annual meetings of the Society for Pediatric Research (1995 to 2013). Selection criteria Only randomized or quasirandomized controlled trials that enrolled preterm infants
Commentary Cochrane in context: Probiotics for prevention of necrotizing enterocolitis in preterm infants Cochrane Review: Probiotics for prevention of necrotizing enterocolitis in preterm infants AlFaleh K, Anabrees J. Probiotics for prevention of necrotizing enterocolitis in preterm infants. Cochrane Database of Systematic Reviews 2014, Issue 4. Art. No.: CD005496. DOI: 10.1002/14651858.CD005496.pub4. This companion piece to the review, “Probiotics for prevention of necrotizing enterocolitis in preterm infants,” contains the following pieces: • The abstract of the review • A commentary from Joan Robinson, editor-in-chief for Evidence-Based Child Health, discussing the importance of this review • A review of clinical practice guidelines • Some other recently published references on this topic
Evidence-Based Child Health: a Cochrane Review Journal is now indexed by MEDLINE (http://www.ncbi. nlm.nih.gov/pubmed) and Scopus (http://www.scopus.com)
Abstract Background Necrotizing enterocolitis (NEC) and nosocomial sepsis are associated with increased morbidity and mortality in preterm infants. Through prevention of bacterial migration across the mucosa, competitive exclusion of pathogenic bacteria and by enhancing the immune responses of the host, prophylactic enteral probiotics (live microbial supplements) may play a role in reducing NEC and the associated morbidity. Objectives To compare the efficacy and safety of prophylactic enteral probiotics administration versus placebo or no treatment in the prevention of severe NEC or sepsis, or both, in preterm infants. Search methods For this update, searches were made of MEDLINE (1966 to October 2013), EMBASE (1980 to October 2013), the Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library (2013, Issue 10), and abstracts of annual meetings of the Society for Pediatric Research (1995 to 2013). Selection criteria Only randomized or quasirandomized controlled trials that enrolled preterm infants
