Original Report: Patient-Oriented, Translational Research American

Journal of

Nephrology

Received: May 13, 2014 Accepted: September 12, 2014 Published online: October 29, 2014

Am J Nephrol 2014;40:345–352 DOI: 10.1159/000368422

Clinical Significance of Chronic Kidney Disease and Atrial Fibrillation on Morbidity and Mortality in Patients with Acute Myocardial Infarction Hyeon Seok Hwang a Mahn-Won Park b Hye Eun Yoon a Yoon Kyung Chang a Chul Woo Yang a Suk Young Kim a Jung Sun Cho b Chan Joon Kim b Gyung-Min Park b Chul-Soo Park b Yun-Seok Choi b Yoon-Seok Koh b Jong Min Lee b Dong Il Shin b Suk Min Seo b Doo Soo Jeon b Keon Woong Moon b Ki Dong Yoo b Hee Yeol Kim b Dong-Bin Kim b Hun-Jun Park b Pum-Joon Kim b Kiyuk Chang b Wook-Sung Chung b Ki-Bae Seung b Myung Ho Jeong c Sung-Ho Her b Youngkeun Ahn c  

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

a Division of Nephrology, b Division of Cardiology, Department of Internal Medicine, The Catholic University of Korea, Seoul, and c Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Korea  

 

 

Abstract Background/Aims: Atrial fibrillation (AF) often coexists with acute myocardial infarction (AMI), and chronic kidney disease (CKD) is a major risk for AMI. However, the combined impact of CKD and AF on the mortality and morbidity in AMI population has not been determined. Methods: Between January 2004 and December 2009, a total of 4,738 AMI patients were enrolled prospectively. Patients were divided into four groups according to the combined status of CKD and AF. The primary endpoint was a combination of 5-year major adverse cardiac and cerebrovascular events (MACCE). Results: The prevalence of AF was significantly higher in CKD patients than in non-CKD patients (6.76 vs. 3.31%, p