Clinical and Electrophysiologic Effects of Magnesium Sulfate on Paroxysmal Supraventricular Tachycardia and Comparison with Adenosine Triphosphate Sami V&kin, MD, Bernard Belhassen,MD, David Sheps, MD, and Shlomo Laniado, MD
Electrophydologtc studies have shown that intravenous magnedum sulfate prolongs atrtoventrfcular (AV) nodal conduction and refractorbress and thus could play a rote in the management of patients with paroxysmal AV reentrant wpraventricular tachycardia (SW). The present study evaluates the clinkal and electrophysiotogic effects of intravenous magnesium sulfate in patients with SVT and compares them with those of adenodne triphosphate (ATP), one of the most potent drugs in the treatment of this arrhythmia. Patients with inducible sustained SVT were treated with ATP (10 or 20 mg) and magneshrm sulfate (2 g over 15 seconds) during etectrophysidogic study. If the tachycardta failed to terminate by the sixth minute, an additional 2 g dose of magnestum was given. ATP (10 or 20 mg) was significantly better than magnestum for termhuutng induced tachycardtas (14 of 14 VI 6 of 14, p
Electrophydologtc studies have shown that intravenous magnedum sulfate prolongs atrtoventrfcular (AV) nodal conduction and refractorbress and thus could play a rote in the management of patients with paroxysmal AV reentrant wpraventricular tachycardia (SW). The present study evaluates the clinkal and electrophysiotogic effects of intravenous magnesium sulfate in patients with SVT and compares them with those of adenodne triphosphate (ATP), one of the most potent drugs in the treatment of this arrhythmia. Patients with inducible sustained SVT were treated with ATP (10 or 20 mg) and magneshrm sulfate (2 g over 15 seconds) during etectrophysidogic study. If the tachycardta failed to terminate by the sixth minute, an additional 2 g dose of magnestum was given. ATP (10 or 20 mg) was significantly better than magnestum for termhuutng induced tachycardtas (14 of 14 VI 6 of 14, p
