Circulating angiogenic and inflammatory cytokine responses to acute aerobic exercise in trained and sedentary young men Rian Q. Landers‑Ramos · Nathan T. Jenkins · Espen E. Spangenburg · James M. Hagberg · Steven J. Prior
Abstract Purpose Endurance exercise training can ameliorate many cardiovascular and metabolic disorders and attenuate responses to inflammatory stimuli. The purpose of this study was to determine whether the angiogenic and pro-inflammatory cytokine response to acute endurance exercise differs between endurance-trained and sedentary young men. Methods Ten endurance-trained and ten sedentary healthy young men performed 30 min of treadmill running at 75 % VO2max with blood sampling before and after exercise. Plasma concentrations of tumor necrosis factor (TNF)alpha, interleukin (IL)-8, IL-6, vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), placental growth factor (PlGF), and soluble VEGF receptor-1 (sFlt-1) were measured by multiplex ELISA. Results Acute exercise increased IL-6 by 165 % (P
Circulating angiogenic and inflammatory cytokine responses to acute aerobic exercise in trained and sedentary young men.
Endurance exercise training can ameliorate many cardiovascular and metabolic disorders and attenuate responses to inflammatory stimuli. The purpose of...