Acta Obstet Gynecol Scand 56: 540, 1977
ANNOUNCEMENT
IIIrd Reinier de Graaf Symposium on non-luteal ovarian function
The third Reinier de G r a d Symposium will be held September 4-6, 1978 in Maastricht, one of the oldest towns, but site of the youngest Medical Faculty in the Netherlands. It will be dedicated to: a. Ovarian follicular morphology and function from intra-uterine life until the onset of puberty.
b. Non-luteal ovarian morphology and function during the period of reproductive capacity. c. Ovarian morphology and function after reproductive age. The Reinier de Graaf lecture will be delivered by Dr. Hannah Peters, Copenhagen. For further information please contact: Prof. Eylard V . van Hall, Department of Obstetrics and Gynaecology, Leiden State University, Leiden, The Netherlands.
Letter to the editor
Dear Sir, In the article “Chorioangioma with hydramnios and intrauterine fetal death” by M. Kuoth et al. in Acta Obstet Gynecol Scand 55: 279, 1976, there is one aspect that I found very interesting. Dr Noth and associates mention that “the placenta was large and oedematous, measuring 2 1 x 20 x 4 cm, weighing 1 150 g”. Placental hypertrophy has been reported associated with chorioangioma, both of the diffuse variety by Potter ( 2 ) and of the localised by Earn & Penner (l), and by Sen (3). The case reported by Dr Knoth and his associates would appear to be unique in having both localised and diffuse chorioangiomas in association with placental hypertrophy. I would in particular like to ask Dr Knoth if they found immature, oedematous villi with small, peripheral non sinusoidal capillaries as was in the last case (3). Certainly there does not seem to be any
Acta Obstet Gynecol Scund 56 (1977)
indication of depressed placental function in these cases, even though villous oedema mimicking hydatidiform mole is sometimes seen. Nevertheless the perinatal mortality is high, probably, as indicated, due to a circulatory overload on the fetal cardiovascular system. The mechanism causing placental hypertrophy and proliferation of immature villi remains obscure. D . K . Sen Dept. of Obstetrics and Gynaecology University of Malaya Kuala Lumpur
REFERENCES 1. Earn, A. A. & Penner, D. W.: Five cases of chorioangioma. J Obstet Gynaecol Br Commonw 57: 442, 1950. 2. Potter, E. L.: Pathology of the Foetus and the Infant. The Year Book Publishers, Chicago, 1961. 3. Sen, D. K . : Placental hypertrophy associated with chorangioma. Am J Obstet GynecollO7: 652, 1970.
ANNOUNCEMENT
IIIrd Reinier de Graaf Symposium on non-luteal ovarian function
The third Reinier de G r a d Symposium will be held September 4-6, 1978 in Maastricht, one of the oldest towns, but site of the youngest Medical Faculty in the Netherlands. It will be dedicated to: a. Ovarian follicular morphology and function from intra-uterine life until the onset of puberty.
b. Non-luteal ovarian morphology and function during the period of reproductive capacity. c. Ovarian morphology and function after reproductive age. The Reinier de Graaf lecture will be delivered by Dr. Hannah Peters, Copenhagen. For further information please contact: Prof. Eylard V . van Hall, Department of Obstetrics and Gynaecology, Leiden State University, Leiden, The Netherlands.
Letter to the editor
Dear Sir, In the article “Chorioangioma with hydramnios and intrauterine fetal death” by M. Kuoth et al. in Acta Obstet Gynecol Scand 55: 279, 1976, there is one aspect that I found very interesting. Dr Noth and associates mention that “the placenta was large and oedematous, measuring 2 1 x 20 x 4 cm, weighing 1 150 g”. Placental hypertrophy has been reported associated with chorioangioma, both of the diffuse variety by Potter ( 2 ) and of the localised by Earn & Penner (l), and by Sen (3). The case reported by Dr Knoth and his associates would appear to be unique in having both localised and diffuse chorioangiomas in association with placental hypertrophy. I would in particular like to ask Dr Knoth if they found immature, oedematous villi with small, peripheral non sinusoidal capillaries as was in the last case (3). Certainly there does not seem to be any
Acta Obstet Gynecol Scund 56 (1977)
indication of depressed placental function in these cases, even though villous oedema mimicking hydatidiform mole is sometimes seen. Nevertheless the perinatal mortality is high, probably, as indicated, due to a circulatory overload on the fetal cardiovascular system. The mechanism causing placental hypertrophy and proliferation of immature villi remains obscure. D . K . Sen Dept. of Obstetrics and Gynaecology University of Malaya Kuala Lumpur
REFERENCES 1. Earn, A. A. & Penner, D. W.: Five cases of chorioangioma. J Obstet Gynaecol Br Commonw 57: 442, 1950. 2. Potter, E. L.: Pathology of the Foetus and the Infant. The Year Book Publishers, Chicago, 1961. 3. Sen, D. K . : Placental hypertrophy associated with chorangioma. Am J Obstet GynecollO7: 652, 1970.
