Asian Spine Journal 472 Panpan Clinical Hu et al. Study
Asian Spine J 2016;10(3):472-479 • http://dx.doi.org/10.4184/asj.2016.10.3.472 Asian Spine J 2016;10(3):472-479
Cerebrospinal Fluid Leakage after Surgeries on the Thoracic Spine: A Review of 362 Cases Panpan Hu*, Miao Yu*, Xiaoguang Liu, Zhongjun Liu, Liang Jiang, Feng Wei, Zhongqiang Chen Department of Orthopedics, Peking University Third Hospital, Beijing, China
Study Design: A retrospective clinical review. Purpose: To describe the incidence of cerebrospinal fluid leakage (CSFL) after thoracic decompression and examine the CSFL predisposing clinical factors. Overview of Literature: CSFL is a common complication following thoracic decompression but has not been sufficiently addressed in former studies. Methods: A cohort of 362 cases of thoracic decompression from February of 2005 to June of 2013 was examined. The case medical records were reviewed and the occurrence of CSFL and the related clinical parameters were noted. The incidence of CSFL for the entire cohort and each surgical approach were described. Besides, the relationship between CSFL and other clinical parameters were assessed, of which odds ratio values of all CSFL-associated parameters were calculated using multivariate logistic regression analysis. Results: The incidence of CSFL for the entire cohort was 32.3%. Different surgical approaches had different incidences of CSFL, and circumferential decompression had the highest incidence. Though many different clinical parameters were related to the occurrences of CSFL, being older than 52 years, having ossification of the posterior longitudinal ligament or having longer operative segments than 3 vertebrae were significant risk factors for CSFL (p 650 (n=215)
82
38.1
p -value
Excluded
0.000a)
2.496
(1.368, 4.553)
0.003b)
0.037a)
1.220
(0.719, 2.070)
0.461
0.042a)
0.591
(0.294, 1.189)
0.140
0.000a)
1.725
(1.008, 2.952)
0.047b)
0.001a)
1.298
(0.708, 2.380)
0.399
0.004a)
1.095
(0.590, 2.033)
0.773
CSF, stands for cerebrospinal fluid; OPLL, ossification of posterior longitudinal ligament; JOA, Japanese Orthopaedic Association; CD, circumferential decompression. a) Accomplished via Pearson’s χ2 test (two-tailed), and p
Asian Spine J 2016;10(3):472-479 • http://dx.doi.org/10.4184/asj.2016.10.3.472 Asian Spine J 2016;10(3):472-479
Cerebrospinal Fluid Leakage after Surgeries on the Thoracic Spine: A Review of 362 Cases Panpan Hu*, Miao Yu*, Xiaoguang Liu, Zhongjun Liu, Liang Jiang, Feng Wei, Zhongqiang Chen Department of Orthopedics, Peking University Third Hospital, Beijing, China
Study Design: A retrospective clinical review. Purpose: To describe the incidence of cerebrospinal fluid leakage (CSFL) after thoracic decompression and examine the CSFL predisposing clinical factors. Overview of Literature: CSFL is a common complication following thoracic decompression but has not been sufficiently addressed in former studies. Methods: A cohort of 362 cases of thoracic decompression from February of 2005 to June of 2013 was examined. The case medical records were reviewed and the occurrence of CSFL and the related clinical parameters were noted. The incidence of CSFL for the entire cohort and each surgical approach were described. Besides, the relationship between CSFL and other clinical parameters were assessed, of which odds ratio values of all CSFL-associated parameters were calculated using multivariate logistic regression analysis. Results: The incidence of CSFL for the entire cohort was 32.3%. Different surgical approaches had different incidences of CSFL, and circumferential decompression had the highest incidence. Though many different clinical parameters were related to the occurrences of CSFL, being older than 52 years, having ossification of the posterior longitudinal ligament or having longer operative segments than 3 vertebrae were significant risk factors for CSFL (p 650 (n=215)
82
38.1
p -value
Excluded
0.000a)
2.496
(1.368, 4.553)
0.003b)
0.037a)
1.220
(0.719, 2.070)
0.461
0.042a)
0.591
(0.294, 1.189)
0.140
0.000a)
1.725
(1.008, 2.952)
0.047b)
0.001a)
1.298
(0.708, 2.380)
0.399
0.004a)
1.095
(0.590, 2.033)
0.773
CSF, stands for cerebrospinal fluid; OPLL, ossification of posterior longitudinal ligament; JOA, Japanese Orthopaedic Association; CD, circumferential decompression. a) Accomplished via Pearson’s χ2 test (two-tailed), and p
