DEVELOPMENTAL MEDICINE & CHILD NEUROLOGY
ORIGINAL ARTICLE
Cerebral oxygenation is associated with neurodevelopmental outcome of preterm children at age 2 to 3 years ELISE A VERHAGEN 1
| KOENRAAD N J A VAN BRAECKEL 1 | CHRISTA N VAN DER VEERE 1 | HENK GROEN 2 | PETER H DIJK 1 | CHRISTIAN V HULZEBOS 1 | AREND F BOS 1 1 Division of Neonatology, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen, Groningen; 2 Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. Correspondence to Elise A Verhagen at Division of Neonatology, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, the Netherlands. E-mail: [email protected] This article is commented on by Austin on pages 404–405 of this issue.
PUBLICATION DATA
Accepted for publication 4th September 2014. Published online 8th November 2014. ABBREVIATIONS
AUC BSID-III
CBCL FTOE GMH-IVH NIRS rcSO2 SES SpO2
Area under the curve Bayley Scales of Infant and Toddler Development, Third Edition Child Behavior Checklist Fractional tissue oxygen extraction Germinal matrix haemorrhage– intraventricular haemorrhage Near-infrared spectroscopy Regional cerebral tissue oxygen saturation Socio-economic status Arterial oxygen saturation
AIM The aim of the study was to determine whether regional cerebral tissue oxygen saturation (rcSO2) and fractional tissue oxygen extraction (FTOE), using near-infrared spectroscopy, are associated with neurodevelopmental outcome of preterm infants. METHOD We measured rcSO2 on days 1, 2, 3, 4, 5, 8, and 15 after birth in 83 preterm infants (
ORIGINAL ARTICLE
Cerebral oxygenation is associated with neurodevelopmental outcome of preterm children at age 2 to 3 years ELISE A VERHAGEN 1
| KOENRAAD N J A VAN BRAECKEL 1 | CHRISTA N VAN DER VEERE 1 | HENK GROEN 2 | PETER H DIJK 1 | CHRISTIAN V HULZEBOS 1 | AREND F BOS 1 1 Division of Neonatology, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen, Groningen; 2 Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. Correspondence to Elise A Verhagen at Division of Neonatology, Beatrix Children’s Hospital, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, the Netherlands. E-mail: [email protected] This article is commented on by Austin on pages 404–405 of this issue.
PUBLICATION DATA
Accepted for publication 4th September 2014. Published online 8th November 2014. ABBREVIATIONS
AUC BSID-III
CBCL FTOE GMH-IVH NIRS rcSO2 SES SpO2
Area under the curve Bayley Scales of Infant and Toddler Development, Third Edition Child Behavior Checklist Fractional tissue oxygen extraction Germinal matrix haemorrhage– intraventricular haemorrhage Near-infrared spectroscopy Regional cerebral tissue oxygen saturation Socio-economic status Arterial oxygen saturation
AIM The aim of the study was to determine whether regional cerebral tissue oxygen saturation (rcSO2) and fractional tissue oxygen extraction (FTOE), using near-infrared spectroscopy, are associated with neurodevelopmental outcome of preterm infants. METHOD We measured rcSO2 on days 1, 2, 3, 4, 5, 8, and 15 after birth in 83 preterm infants (
