Cells to Surgery Quiz
Cells to Surgery Quiz: January 2015 Leyre Falto-Aizpurua1, Brian J. Simmons1, Robert D. Griffith1, Mohammad-Ali Yazdani Abyaneh1 and Keyvan Nouri1 Journal of Investigative Dermatology (2015) 135, e9. doi:10.1038/jid.2014.474
JID and Logical Images, Inc., have cooperated to offer the Cells to Surgery Quiz, incorporating diagnostic images from VisualDx’s vast database. Questions relate to the image as well as to selected articles in JID, which are listed after the questions. Answers will be posted as supplementary material. We hope you enjoy this challenge.
Image appears with permission from VisualDx. © Logical Images, Inc.
Questions 1. A 59-year-old woman presents to your clinic with the lesions shown above, which have slowly increased in size and number over the past few months. Because of her job, it is difficult for her to coordinate regular follow-up visits. Which of the following would provide the best treatment option for this patient, who is poorly compliant with medications and lacks the ability to follow up regularly? a. Photodynamic therapy. b. Cryotherapy. c. Oral isotretinoin. d. Topical tretinoin.
Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA
1
© 2015 The Society for Investigative Dermatology
www.jidonline.org
1
Cells to Surgery Quiz
2. Jung et al. observed normal sebaceous gland function using coherent anti–Stokes Raman scattering (CARS) microscopy. Which of the following would you expect to see with in vivo imaging CARS microscopy? a. Holocrine secretion of sebaceous glands. b. Centrifugal migration of sebocytes. c. Three-dimensional longitudinal imaging of the sebaceous glands. d. All of the above.
3. After discussing possible treatment options with the patient, you both decide to treat the lesions with cryotherapy. Which of the following would be an expected in vivo effect that would be observed in sebaceous glands after cryotherapy? a. Destruction of sebocytes’ intracellular structures. b. Destruction of central sebocytes before peripheral sebocytes. c. Permanent gland destruction. d. Increased lipid excretion into the infundibulum. e. None of the above.
TOPIC ARTICLE The questions refer to the following article: Jung Y, Tam J, Jalian HR et al. (2015) Longitudinal, 3D in vivo imaging of sebaceous glands by coherent anti–Stokes Raman scattering microscopy: normal function and response to cryotherapy. J Invest Dermatol 135:39–44
Answers are available as supplementary material at http://dx.doi.org/10.1038/jid.2014.474.
2
Journal of Investigative Dermatology (2015), Volume 135
Copyright of Journal of Investigative Dermatology is the property of Nature Publishing Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use.
Cells to Surgery Quiz: January 2015 Leyre Falto-Aizpurua1, Brian J. Simmons1, Robert D. Griffith1, Mohammad-Ali Yazdani Abyaneh1 and Keyvan Nouri1 Journal of Investigative Dermatology (2015) 135, e9. doi:10.1038/jid.2014.474
JID and Logical Images, Inc., have cooperated to offer the Cells to Surgery Quiz, incorporating diagnostic images from VisualDx’s vast database. Questions relate to the image as well as to selected articles in JID, which are listed after the questions. Answers will be posted as supplementary material. We hope you enjoy this challenge.
Image appears with permission from VisualDx. © Logical Images, Inc.
Questions 1. A 59-year-old woman presents to your clinic with the lesions shown above, which have slowly increased in size and number over the past few months. Because of her job, it is difficult for her to coordinate regular follow-up visits. Which of the following would provide the best treatment option for this patient, who is poorly compliant with medications and lacks the ability to follow up regularly? a. Photodynamic therapy. b. Cryotherapy. c. Oral isotretinoin. d. Topical tretinoin.
Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA
1
© 2015 The Society for Investigative Dermatology
www.jidonline.org
1
Cells to Surgery Quiz
2. Jung et al. observed normal sebaceous gland function using coherent anti–Stokes Raman scattering (CARS) microscopy. Which of the following would you expect to see with in vivo imaging CARS microscopy? a. Holocrine secretion of sebaceous glands. b. Centrifugal migration of sebocytes. c. Three-dimensional longitudinal imaging of the sebaceous glands. d. All of the above.
3. After discussing possible treatment options with the patient, you both decide to treat the lesions with cryotherapy. Which of the following would be an expected in vivo effect that would be observed in sebaceous glands after cryotherapy? a. Destruction of sebocytes’ intracellular structures. b. Destruction of central sebocytes before peripheral sebocytes. c. Permanent gland destruction. d. Increased lipid excretion into the infundibulum. e. None of the above.
TOPIC ARTICLE The questions refer to the following article: Jung Y, Tam J, Jalian HR et al. (2015) Longitudinal, 3D in vivo imaging of sebaceous glands by coherent anti–Stokes Raman scattering microscopy: normal function and response to cryotherapy. J Invest Dermatol 135:39–44
Answers are available as supplementary material at http://dx.doi.org/10.1038/jid.2014.474.
2
Journal of Investigative Dermatology (2015), Volume 135
Copyright of Journal of Investigative Dermatology is the property of Nature Publishing Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use.
