Cell Line: 2004–2014 First Resource
First Theory article
Cell gets a new look: Leading Edge is born
PaperFlicks: authors on camera
Cell tweets
Lady Gaga parody goes viral – “I want good data. A paper in Cell.”
MicroRNA biology Bartel Vol. 116, 281–297
Voices shares scientific perspectives
Cell joins Facebook nation Genome editing in a nonhuman primate
Pluripotent SCs from human fibroblasts Yamanaka Vol. 131, 861–872
"This paper proposed the notion that immune ignorance to the microbiota, the prevailing theory at the time, may not hold true in all cases."
Carbon dating the brain Frisén Vol. 122, 133–143
2005
NF-κB links inflammation and cancer
2006
Tishkoff Vol. 150, 457–469
2007 High-resolution view on DNA methylation
2008 PaperClips debut
2009
2010
Defining supplementary material
2011
2013
Rapid genome editing in mice
Jaenisch Vol. 154, 1370–1379
2014
Beige adipocytes
Cell Picture Show celebrates beauty in science
Spiegelman Vol. 150, 366–376
Mouse cortical connectomics
Tetherin ligates HIV
Dong Vol. 156, 1096–1111
Hallmarks of Cancer for a new decade
Bieniasz Vol. 139, 499–511
Chen Vol. 122, 669–682
2012
Human somatic cell nuclear transfer Mitalipov Vol. 153, 1228–1238
Evolutionary history from whole-genome sequences of hunter-gatherers
Discovery of MAVS
Karin Vol. 118, 285–296
Hanahan and Weinberg Vol. 144, 646–674
Histone demethylase Shi Vol. 119, 941–953 AC
"The inability to see global demethylation by LSD1… demonstrates the gene specific nature of demethylation...."
RORγT master of Th17 cells
Cua and Littman Vol. 126, 1121–1133 AC
lncRNAs in HOX regulation
Rinn and Chang Vol. 129, 1311–1323 AC
"Peter Campbell and colleagues made a truly remarkable observation noting cancer genomes in which DNA rearrangements occurred in a highly focal manner - with many DNA rearrangements basically arising on a single chromosome."
Computational model for an entire cell Personal 'omics'
Snyder Vol. 148, 1293–1307
Covert Vol. 150, 389–401
cGAMP generation and immune function Base-resolution sequencing of 5hmC Ren Vol. 149, 1368–1380
Patel Vol. 153, 1094–1107 Vol. 154, 748–762
ES
OF EXCIT
I
40 SI
NCE 1974
B I O LOGY
"Another surprising result: the first demonstration that a long noncoding RNA can act in trans to regulate a chromatin domain."
Stratton, Futreal, and Campbell Vol. 144, 27–40 AC
NG
“…the claim that Th17 cells were a distinct population met with much skepticism…. [T]hat an orphan nuclear receptor RoRγt was the transcription factor required for the differentiation of Th17 cells from that common progenitor resolved that controversy.”
Chromothripsis
D
Zhao Vol. 132, 887–898
U R DE CA
ChIP-seq for hi-res nucleosome positioning
Nobel Prize
McKnight Vol. 149, 753–767 Vol. 149, 768–779
"The finding that iPSCs could also be derived from adult tail tip fibroblasts nailed this story."
Jacobsen and Ecker Vol. 126, 1189–1201
LEGEND
RNA granules as hydrogels
Settleman Vol. 141, 69–80
Takahashi and Yamanaka Vol. 126, 663–676 AC
Open archive
Landmark Paper Essential Review Cell Milestone Publishing Innovation AC Annotated Classic
Cancer cells sample drug-tolerant state
Wagers and Lee Vol. 153, 828–839
FO
2004
Articles enhanced!
Four factors reprogram mouse fibroblasts
Medzhitov Vol. 118, 229–241 AC
Circulating factor reverses cardiac aging phenotype
Alt and Dekker Vol. 148, 908–921
SnapShot Microbiota maintains host homeostasis
Sha Vol. 156, 836–843
Spatial organization of the mouse genome