Cardiovascular and Endocrine Profile of Adrenergic Neurone Blockade in Normal and Hypertensive Man

JOSEF

FLAMMER,

PETER ZEEV

GLijCK.

WALTER FRANCOIS

Some cardiovascular and endocrine effects of adrenergic blockade were assessed in six normal subjects, six patients with mild hypertension (diastolic pressure -300 mm Hg) and six patients with moderate to severe essential hypertension. Administration of the inhibitory agent, debrisoquine, for six weeks markedly decreased supine and upright plasma norepinephrine levels, and norepinephrine excretion in all three groups. Supine and upright blood pressure was decreased more (p

Cardiovascular and endocrine profile of adrenergic neurone blockade in normal and hypertensive man.

Cardiovascular and Endocrine Profile of Adrenergic Neurone Blockade in Normal and Hypertensive Man JOSEF FLAMMER, PETER ZEEV GLijCK. WALTER FRANC...
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