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OPEN
Received: 11 November 2016 Accepted: 3 May 2017 Published: xx xx xxxx
Canine Leishmaniasis Progression is Associated with Vitamin D Deficiency A. Rodriguez-Cortes1, C. Martori1, A. Martinez-Florez1, A. Clop 2, M. Amills2, J. Kubejko2, J. Llull3, J. M. Nadal3 & J. Alberola1 The relationship between vitamin D deficiency and the risk of suffering from a plethora of health disorders, ranging from autoimmune processes to infectious diseases has been widely described. Nonetheless, the potential role of vitamin D in visceral leishmaniasis remains uncharacterized. In the Mediterranean basin, where the dog is leishmania’s main peri-domestic reservoir, control measures against the canine disease have shown beneficial effects on the incidence of human leishmaniasis. In this study, we measured the vitamin D levels in serum samples from a cohort of 68 healthy and disease dogs from a highly endemic area and we have also studied the relationship of these levels with parasitological and immunological parameters. The sick dogs presented significantly lower (P
OPEN
Received: 11 November 2016 Accepted: 3 May 2017 Published: xx xx xxxx
Canine Leishmaniasis Progression is Associated with Vitamin D Deficiency A. Rodriguez-Cortes1, C. Martori1, A. Martinez-Florez1, A. Clop 2, M. Amills2, J. Kubejko2, J. Llull3, J. M. Nadal3 & J. Alberola1 The relationship between vitamin D deficiency and the risk of suffering from a plethora of health disorders, ranging from autoimmune processes to infectious diseases has been widely described. Nonetheless, the potential role of vitamin D in visceral leishmaniasis remains uncharacterized. In the Mediterranean basin, where the dog is leishmania’s main peri-domestic reservoir, control measures against the canine disease have shown beneficial effects on the incidence of human leishmaniasis. In this study, we measured the vitamin D levels in serum samples from a cohort of 68 healthy and disease dogs from a highly endemic area and we have also studied the relationship of these levels with parasitological and immunological parameters. The sick dogs presented significantly lower (P
