Accepted Manuscript Can we use serum copeptin levels as a biomarker in obstructive sleep apnea syndrome? Dr. Omer Tarık Selcuk, Dr. Mete Eyigor, Assoc. Prof., Dr. Levent Renda, Dr. Ustun Osma, Assoc. Prof., Dr. Hulya Eyigor, Assoc. Prof., Dr. Nursel Turkoglu Selcuk, Dr. Mustafa Deniz Yılmaz, Assoc. Prof., Dr. Cansu Demirkıran, Hande Unlu, PhD, Dr. Meral Gültekin, Prof. PII:
S1010-5182(15)00085-2
DOI:
10.1016/j.jcms.2015.03.031
Reference:
YJCMS 2014
To appear in:
Journal of Cranio-Maxillo-Facial Surgery
Received Date: 8 July 2014 Revised Date:
16 February 2015
Accepted Date: 25 March 2015
Please cite this article as: Selcuk OT, Eyigor M, Renda L, Osma U, Eyigor H, Selcuk NT, Yılmaz MD, Demirkıran C, Unlu H, Gültekin M, Can we use serum copeptin levels as a biomarker in obstructive sleep apnea syndrome?, Journal of Cranio-Maxillofacial Surgery (2015), doi: 10.1016/ j.jcms.2015.03.031. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT Can we use serum copeptin levels as a biomarker in obstructive sleep apnea syndrome?
Dr. Omer Tarık Selcuk1, Assoc. Prof. Dr. Mete Eyigor2, Dr. Levent Renda1, Assoc. Prof. Dr.
RI PT
Ustun Osma1, Assoc. Prof. Dr. Hulya Eyigor1, Dr.Nursel Turkoglu Selcuk3, Assoc. Prof. Dr. Mustafa Deniz Yılmaz1, Dr. Cansu Demirkıran1, Hande Unlu, PhD4, Prof. Dr. Meral
Antalya Research and Teaching Hospital ENT Department 2
Adnan Menderes University Microbiology Department
Antalya Research and Teaching Hospital Pulmonary Medicine and Sleep Department
4
Hacettepe University, The institute of Public Health 5
TE D
3
M AN U
1
SC
Gültekin5
Akdeniz University Microbiology Department
EP
Corresponding Author: Dr.Ömer Tarık Selçuk
AC C
Antalya Education and Research Hospital, ENT Clinic Antalya / Türkiye e-mail:[email protected] tel.no: 05333254432
There is no conflict of interest.
ACCEPTED MANUSCRIPT Summary Objective: The aim of this study was to compare serum copeptin levels in patients with obstructive sleep apnea syndrome (OSA) and simple snorers without sleep apnea; and to investigate relationships between copeptin levels and polysomnographic parameters.
RI PT
Methods: Serum copeptin levels were determined using enzyme-linked immunosorbent assay in 47 patients with OSA and 12 patients without OSA (control group). Full-night
polysomnography was performed in each patient. Patients with OSA were divided into three
moderate OSA (15
S1010-5182(15)00085-2
DOI:
10.1016/j.jcms.2015.03.031
Reference:
YJCMS 2014
To appear in:
Journal of Cranio-Maxillo-Facial Surgery
Received Date: 8 July 2014 Revised Date:
16 February 2015
Accepted Date: 25 March 2015
Please cite this article as: Selcuk OT, Eyigor M, Renda L, Osma U, Eyigor H, Selcuk NT, Yılmaz MD, Demirkıran C, Unlu H, Gültekin M, Can we use serum copeptin levels as a biomarker in obstructive sleep apnea syndrome?, Journal of Cranio-Maxillofacial Surgery (2015), doi: 10.1016/ j.jcms.2015.03.031. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT Can we use serum copeptin levels as a biomarker in obstructive sleep apnea syndrome?
Dr. Omer Tarık Selcuk1, Assoc. Prof. Dr. Mete Eyigor2, Dr. Levent Renda1, Assoc. Prof. Dr.
RI PT
Ustun Osma1, Assoc. Prof. Dr. Hulya Eyigor1, Dr.Nursel Turkoglu Selcuk3, Assoc. Prof. Dr. Mustafa Deniz Yılmaz1, Dr. Cansu Demirkıran1, Hande Unlu, PhD4, Prof. Dr. Meral
Antalya Research and Teaching Hospital ENT Department 2
Adnan Menderes University Microbiology Department
Antalya Research and Teaching Hospital Pulmonary Medicine and Sleep Department
4
Hacettepe University, The institute of Public Health 5
TE D
3
M AN U
1
SC
Gültekin5
Akdeniz University Microbiology Department
EP
Corresponding Author: Dr.Ömer Tarık Selçuk
AC C
Antalya Education and Research Hospital, ENT Clinic Antalya / Türkiye e-mail:[email protected] tel.no: 05333254432
There is no conflict of interest.
ACCEPTED MANUSCRIPT Summary Objective: The aim of this study was to compare serum copeptin levels in patients with obstructive sleep apnea syndrome (OSA) and simple snorers without sleep apnea; and to investigate relationships between copeptin levels and polysomnographic parameters.
RI PT
Methods: Serum copeptin levels were determined using enzyme-linked immunosorbent assay in 47 patients with OSA and 12 patients without OSA (control group). Full-night
polysomnography was performed in each patient. Patients with OSA were divided into three
moderate OSA (15
