Campylobacter Prosthetic Joint Infection

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Shawn Vasoo, Jeramy J. Schwab, Scott A. Cunningham, Trisha J. Robinson, Joseph R. Cass, Elie F. Berbari, Randall C. Walker, Douglas R. Osmon and Robin Patel J. Clin. Microbiol. 2014, 52(5):1771. DOI: 10.1128/JCM.03572-13. Published Ahead of Print 12 February 2014.

CASE REPORT

Campylobacter Prosthetic Joint Infection Shawn Vasoo,a Jeramy J. Schwab,b Scott A. Cunningham,b Trisha J. Robinson,c Joseph R. Cass,d Elie F. Berbari,a Randall C. Walker,a Douglas R. Osmon,a Robin Patela,b

A 75-year-old man was diagnosed with probable Campylobacter jejuni prosthetic knee infection after a diarrheal illness. Joint aspirate and operative cultures were negative, but PCR of prosthesis sonicate fluid was positive, as was stool culture. Nineteen additional cases of Campylobacter prosthetic joint infection reported in the literature are reviewed.

CASE REPORT

A

75-year-old man from Minnesota presented with a 6-day history of right knee pain and swelling. He had a history of bilateral knee arthroplasties performed 4 years prior, hypertension, and papillary thyroid cancer. Two years prior, he developed culture-negative right prosthetic knee joint infection (PJI), which was managed at another facility with two-stage resection-reimplantation of his right knee prosthesis. He had been doing well since then. One day before his current onset of knee pain, he developed acute, nonbloody diarrhea. He worked on a cattle farm but had no direct contact with animals, had no recent travel, did not recall consuming undercooked meats, and had no ill contacts. He was evaluated by his local doctors 3 days into his diarrheal illness. Stool was positive for Campylobacter antigen (ImmunoCard STAT! CAMPY; Meridian Bioscience, Cincinnati, OH). He was treated with oral azithromycin for 3 days. His diarrhea improved, but knee pain persisted and was associated with subjective fevers and chills. On the fifth day of illness, he presented to his local orthopedic surgeon and underwent right knee aspiration, which showed 27,900 leukocytes/␮l (88% neutrophils). The following day, he presented to our facility with a warm and tender right knee and a large effusion. Right knee aspiration yielded 127 ml of “brown murky” fluid with 42,681 leukocytes/␮l (92% neutrophils). The C-reactive protein (CRP) level and erythrocyte sedimentation rate (ESR) were 239 mg/liter and 47 mm/h, respectively. Gram stain of the aspirated fluid was negative, as were bacterial cultures (aerobic cultures on sheep blood and chocolate agar, anaerobic cultures in thioglycolate broth and on CDC sheep blood agar, and Campylobacter cultures under microaerophilic conditions on cefoperazone-vancomycin-amphotericin B [CVA] and buffered charcoal yeast extract [BCYE] agar) at 42°C and fungal and mycobacterial cultures, along with blood cultures. The patient underwent resection arthroplasty with placement of a vancomycin- and gentamicin-impregnated antibiotic spacer. Acute inflammation was present in periprosthetic tissue. Aerobic, anaerobic, and microaerophilic cultures (at 42°C) performed on two periprosthetic tissues and prosthesis sonicate fluid (1) were negative. A previously described Campylobacter jejuni/Campylobacter coli real-time PCR assay targeting cadF and designed for testing stool (2) was performed on sonicate fluid. The PCR assay was positive, with a crossing point value of 37.6 cycles (positivecontrol crossing point, 32.0 cycles). He was treated with intravenous meropenem (1 g every 8 h) and oral azithromycin (500 mg

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daily) for 6 weeks. The Campylobacter antigen-positive stool specimen collected at his local health care facility was forwarded to the Minnesota Department of Health, where Campylobacter jejuni was isolated. The isolate exhibited a positive hippurate hydrolysis reaction and was susceptible by the Etest to ciprofloxacin and erythromycin but resistant to tetracycline (3). Using National Antimicrobial Resistance Monitoring System (NARMS) criteria, the isolate was also susceptible to nalidixic acid, clindamycin, gentamicin, chloramphenicol, and azithromycin (4). After completion of meropenem and azithromycin, he was maintained on azithromycin for another 7 weeks, and then observed off therapy for 4 weeks prior to reimplantation arthroplasty. Bacterial cultures and cadF PCR of three tissue specimens obtained at the time of reimplantation were negative, although histopathology showed residual acute inflammation. Postreimplantation, he was treated with meropenem for 2 weeks, and thereafter, chronic suppressive therapy with oral azithromycin at 1,200 mg weekly was administered. The patient remained well at 3 months of follow-up.

By 2030, the yearly number of combined knee and hip arthroplasties is estimated to reach 4 million (5), and recent data have shown that laboratory-confirmed campylobacteriosis increased by 14% in 2012, compared to 2006 to 2008 (6). While Campylobacter PJI is an uncommon entity, the convergence of two factors—an increased numbers of persons with prosthetic joints and the prominence of food-borne infections despite stringent regulatory measures (5, 42)—makes it likely that clinicians will continue to encounter PJIs caused by enteropathogens (7, 8). We reviewed the literature regarding Campylobacter PJI. Twenty cases (including our case) have been reported (9–20) (Table 1). One case reported as “Campylobacter intestinalis” was excluded as we were unable to obtain further details (21). The predominance of C. fetus is in keeping with its propensity to cause

Received 23 December 2013 Returned for modification 21 January 2014 Accepted 3 February 2014 Published ahead of print 12 February 2014 Editor: W. M. Dunne, Jr. Address correspondence to Robin Patel, [email protected]. Copyright © 2014, American Society for Microbiology. All Rights Reserved. doi:10.1128/JCM.03572-13

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Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USAa; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USAb; Acute Disease Investigation and Control Section, Minnesota Department of Health, St. Paul, Minnesota, USAc; Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USAd

Case Report

TABLE 1 Campylobacter prosthetic joint infections reported in the literaturea No. (%) of male patients

Relevant exposure (no.)

No. (%) immunocompromised

Joint (no.)

Time of onset of PJI from arthroplasty

C. fetus

13

72 (52–88)

6 (46)

Cattle farmer (1)

9 (69)d

Knee (5),e hip (8)

C. jejuni

3

75 (60–77)

3 (100)

Cattle farmer (1)

1 (33)d

C. coli

1

60

1 (100)

C. gracilis

1

74

1 (100)

Consumed raw oysters (1) Cattle farmer who handled septic abortion (1)

C. lari

1

81

1 (100)

C. upsaliensis

1

24

1 (100)

Acuity (no.)

Diarrheal illness

1 mo–⬃8 yrf

Acute (4), chronic (8), Unk (1)

Yes (4), no (4), Unk (5)

Knee (2) Hip (1)

2–9 yrg

Acute (2), chronic (1)

0

Hip

6 yr

Acute

Yes (2), Unk (1) Yes

0

Knee

3 yr

Acute

Yes

Hip

4 yr

Acute

No

Knee

1 yr

Acute

Yes

0 1 (100)

d

a

Abbreviations: PJI, prosthetic joint infection; Pos, positive; Neg, negative; Unk, unknown; ND, not done; 1SR, one-stage reimplantation arthroplasty; 2SR, two-stage reimplantation arthroplasty; DAIR, débridement, antibiotics, and implant retention; NR, not recorded; NA, not applicable. b Combination therapy represents simultaneous treatment with two or more classes of antimicrobials at any time point. c Excluding patients placed on chronic antibiotic suppression. d These comprised: C. fetus (liver cirrhosis, 3; lung cancer, 1; renal transplant, 1; rheumatoid arthritis on immunosuppressants, 2; chronic leukemia, 2); C. jejuni (AIDS and liver cirrhosis); and C. upsaliensis (tibial osteoblastic osteosarcoma). e Bilateral prosthetic knee joints were involved in one case. f Data from seven cases with onsets of PJI of 1, 5, and 11 months and 3 (Alain Meyer, personal communication), 4, 7, and ⬃8 years. g Data from two cases. h Two specimens comprised drainage from wound and a bone biopsy specimen. i This is the present case. PCR for cadF was positive, but cultures were negative. j Two patients underwent DAIR, two patients did not undergo surgery, and one patient underwent a two-stage revision. k One death from an unrelated cause.

bacteremia, possibly related to its relative resistance to the bactericidal activity of serum (22). There has been a male preponderance (65%) of Campylobacter PJI, with patients having a median age of 72 years (range, 24 to 88 years), and with cases relatively equally distributed between hip and knee prostheses. Seventy percent of patients with C. fetus PJI have been immunocompromised (three with liver cirrhosis, two each with chronic leukemia and rheumatoid arthritis on immunosuppressive therapy, and one each with lung cancer and renal transplant). Interestingly three patients with Campylobacter PJI (including our patient) were cattle farmers, suggesting zoonotic transmission. Onset of PJI following arthroplasty has been as short as 1 month (in a patient who had campylobacteriosis perioperatively, with positive blood and stool cultures) and as long as 9 years (median, 3 years). Among patients with available data, 53% (10/ 19) presented acutely, the remainder having more protracted symptoms, and 69% (9/13) reporting a diarrheal illness preceding their episode of PJI. Together, these data suggest that Campylobacter PJI likely arises following hematogenous seeding of the site of the prosthetic joint after a gastrointestinal illness, which may or may not be symptomatic. Of the 20 cases, 8 (40%) and 5 (25%) had positive blood and stool cultures, respectively, although results of these cultures were not obtained and/or not reported in all cases. The yield of stool cultures may be low for certain Campylobacter spp.: C. fetus and C. upsaliensis may be inhibited by cephalothin-containing Campylobacter selective media, and C. fetus may not grow well at the 42°C incubation temperature routinely used for isolation of C. jejuni (23). With the exception of our case, all reported cases of Campylobacter PJI have had positive cultures from the affected joint, including cultures of synovial fluid, bone, tissue, or wound drainage. A variety of surgical strategies (including one- or two-stage

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resection arthroplasties or débridement, antibiotics, and implant retention [DAIR]) and antimicrobial regimens have been employed for the management of Campylobacter PJI, with most cases of C. fetus and C. jejuni PJIs treated with a combination of antimicrobials. Overall, the usage of the various antimicrobial classes has included the following: ␤-lactams (including ␤-lactam/␤-lactam inhibitor combinations and carbapenems), 60%; aminoglycosides, 55%; macrolides, 45%; fluoroquinolones, 25%; clindamycin, 25%; and tetracyclines, 10%. Despite heterogeneous treatment, most cases have had a successful outcome, although the duration of follow-up has been variable (Table 1). Five cases were managed with no surgery and seven with DAIR. Of these, one patient with Campylobacter lari PJI (19) managed with DAIR succumbed to sepsis on the second day of hospital admission, and a second patient with C. fetus PJI managed with antimicrobial agents alone died of an unrelated cause 2 months following presentation. While these numbers are too small to draw firm conclusions, it is interesting that the remaining 10 cases were successfully managed, with four patients (2 each managed with DAIR and no surgery) being maintained on chronic suppressive antimicrobial therapy. Our case highlights several points. First, special growth requirements may preclude Campylobacter spp. from being routinely isolated. Thus, when there is a compatible clinical syndrome (i.e., preceding diarrhea), clinicians should alert the clinical microbiology laboratory to the possibility of Campylobacter infection so that appropriate culture media and incubation conditions are used. Studies on extra-articular specimens (e.g., blood and stool cultures, stool antigen testing, and PCR) may be useful adjuncts in diagnosing campylobacteriosis. Although early treatment of gastrointestinal disease may prevent hematogenous dissemination and subsequent PJI, antimicrobial agents can render

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Species

No. of cases

Median patient age, yr (range)

Case Report

TABLE 1 (Continued) Culture result (no.) Blood

Stool

Joint

Pos (5), Neg (6), Pos (4), Neg (4), Pos (13)h Unk (2) ND (2), Unk (3)

Surgery (no.)

No. (%) with No. (%) with combination Duration of chronic b c treatment therapy suppression Outcome (no.) 4 (31)j

Recovered (11), death (2)k

6 mo–5 yr (8 cases)

9–15

8–22 wk

1 (33)i

Recovered (3)

7 wk–8 yr

6 wk

0

Recovered

NR

9, 16; this report 17

1

⬃8 wk

0

Recovered

6 mo

18

DAIR

1

NA

NA

No surgery

1

30 wk

0

Death from sepsis NR at 2 days Recovered 34 mo

Neg

Pos (1), Neg (1), Pos (2), Neg (1)i ND (1) ND Pos

Pos

Neg

Pos

DAIR

Pos

Neg

Pos

Neg

Neg

Pos

cultures obtained for diagnosis of PJI negative. Recent Infectious Diseases Society of America (IDSA) guidelines (24) recommend avoiding antimicrobial agents if feasible or holding them for at least 2 weeks prior to collection of cultures for PJI diagnosis. It may not be possible to administer antimicrobial agents so as to idealize both scenarios. Second, molecular testing, in this case using a real-time PCR assay on sonicate fluid, may be useful in defining the etiology of PJI. Arguably, the mere detection of bacterial DNA in sonicate fluid may not amount to definitive evidence for PJI (25), as DNA of urogenital and enteric pathogens (Chlamydia and Yersinia species, respectively) has been detected in synovial fluid of patients with reactive arthritis (26). However, our patient fulfilled the IDSA criteria for PJI (given gross purulence of synovial fluid and acute inflammation on histopathology) (24) and also had a concurrent stool culture positive for C. jejuni. Pre- and intraoperative cultures from his joint may have been rendered negative due to antecedent antimicrobial therapy. Thus, the positive cadF PCR in our patient corroborates a probable diagnosis of C. jejuni PJI. Nevertheless, it cannot be definitely concluded that C. jejuni was the cause of the PJI, since no viable isolate was recovered from the site of his prosthetic joint. Microorganisms associated with PJI are found in biofilms; thus, methods such as implant vortexing and sonication, which sample the prosthesis surface, provide improved sensitivity for PJI diagnosis compared to conventional periprosthetic tissue cultures (1). Molecular methods further improve the sensitivity of biofilm-directed diagnostic approaches. We recently compared results from a PCR panel of 10 individual PCR assays targeting (at the genus or group level) the most common bacteria that cause PJIs, performed on biofilms dislodged from explanted hip and knee arthroplasties, and found that the sensitivities of tissue culture, sonicate fluid culture, and sonicate PCR were 70.1, 72.9, and 77.1%, respectively (27). We have also investigated PCR-electrospray ionization mass spectrometry (28) and 16S rRNA gene real-time PCR (29) on sonicate fluid for the diagnosis of PJI and found both techniques to be at least as sensitive as (29) or superior to (28) culture-based methods, with improved turnaround time. Finally, based on our review of the literature, we propose that clinicians promptly diagnose and probably treat campylobacteriosis and other enteric bacterial infections in patients with prosthetic joints, as their implants may be considered “locus minoris

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resistentiae” (30, 31). As illustrated in the report by Prendki et al. of two postoperative Campylobacter PJI cases occurring after recent gastroenteritis (9), consideration should be given to postponing elective arthroplasty surgery in patients who have had a recent episode of bacterial gastroenteritis. PJIs caused by non-Campylobacter enteric pathogens have included Yersinia enterocolitica (32–34), Salmonella species (over 20 cases reported) (35), and Clostridium difficile (36–39). Although current treatment recommendations for campylobacteriosis limit treatment to those with severe illness, protracted symptoms (⬎1 week), and the immunocompromised (40, 41), based on the findings reported herein, treatment might also be considered for those with prosthetic joints because patients with prosthetic joints may have a predilection to developing PJI after what may initially seem like an innocuous gastrointestinal illness. Future studies should address the risk of PJI in patient who have a prosthetic joint and an infection with a bacterial enteric pathogen, including Campylobacter species. ACKNOWLEDGMENTS Robin Patel is supported by research grants from the National Institutes of Health (R01 AR056647 and R01 AI91594). Robin Patel has received research grant support from Pfizer, Pocared, Pradama, Astellas, 3M, and Tornier. She has patents for a pertussis PCR assay, an antibiofilm substance, and a method/device for sonication. She has relinquished her rights to receive royalties for the sonication device. We thank Alain Meyer for providing further clinical details from a case he reported (15).

REFERENCES 1. Trampuz A, Piper KE, Jacobson MJ, Hanssen AD, Unni KK, Osmon DR, Mandrekar JN, Cockerill FR, Steckelberg JM, Greenleaf JF, Patel R. 2007. Sonication of removed hip and knee prostheses for diagnosis of infection. N. Engl. J. Med. 357:654 – 663. http://dx.doi.org/10.1056 /NEJMoa061588. 2. Cunningham SA, Sloan LM, Nyre LM, Vetter EA, Mandrekar J, Patel R. 2010. Three-hour molecular detection of Campylobacter, Salmonella, Yersinia, and Shigella species in feces with accuracy as high as that of culture. J. Clin. Microbiol. 48:2929 –2933. http://dx.doi.org/10.1128/JCM .00339-10. 3. CLSI. 2010. Methods for antimicrobial dilution and disk susceptibility testing of infrequently isolated or fastidious bacteria; approved guideline, 2nd ed. CLSI document M45-A2. Clinical and Laboratory Standards Institute, Wayne, PA. 4. Centers for Disease Control and Prevention. 2011. National antimicrobial resistance monitoring system: enteric bacteria, 2011 annual report.

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4–12 wk

1SR (3), 1SR and DAIR (1), 12 (92) 2SR (1), DAIR (3), explantation (1), no surgery (3), NR (1) 1SR (1), 2SR (1), no 3 (100) surgery (1) DAIR 0

Pos (1), Neg (2)

Duration of follow-up Reference(s)

Case Report

5.

6.

8.

9. 10. 11. 12. 13.

14.

15.

16. 17. 18. 19.

20.

21.

22. 23.

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24. Osmon DR, Berbari EF, Berendt AR, Lew D, Zimmerli W, Steckelberg JM, Rao N, Hanssen A, Wilson WR. 2013. Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America. Clin. Infect. Dis. 56:e1– e25. http://dx.doi.org /10.1093/cid/cis803. 25. Taylor-Robinson D, Keat A. 1999. Septic and aseptic arthritis: a continuum? Bailliere’s Best Pract. Res. Clin. Rheumatol. 13:179 –192. http://dx .doi.org/10.1053/berh.1999.0013. 26. Pope JE, Krizova A, Garg AX, Thiessen-Philbrook H, Ouimet JM. 2007. Campylobacter reactive arthritis: a systematic review. Semin. Arthritis Rheum. 37:48 –55. http://dx.doi.org/10.1016/j.semarthrit.2006.12.006. 27. Cazanave C, Greenwood-Quaintance KE, Hanssen AD, Karau MJ, Schmidt SM, Gomez Urena EO, Mandrekar JN, Osmon DR, Lough LE, Pritt BS, Steckelberg JM, Patel R. 2013. Rapid molecular microbiologic diagnosis of prosthetic joint infection. J. Clin. Microbiol. 51:2280 –2287. http://dx.doi.org/10.1128/JCM.00335-13. 28. Greenwood-Quaintance KE, Uhl JR, Hanssen AD, Sampath R, Mandrekar JN, Patel R. 2014. Diagnosis of prosthetic joint infection (PJI) using polymerase chain reaction-electrospray ionization mass spectrometry (PCR-ESI/MS). J. Clin. Microbiol. 52:642– 649. http://dx.doi.org/10 .1128/JCM.03217-13. 29. Gomez E, Cazanave C, Cunningham SA, Greenwood-Quaintance KE, Steckelberg JM, Uhl JR, Hanssen AD, Karau MJ, Schmidt SM, Osmon DR, Berbari EF, Mandrekar J, Patel R. 2012. Prosthetic joint infection diagnosis using broad-range PCR of biofilms dislodged from knee and hip arthroplasty surfaces using sonication. J. Clin. Microbiol. 50:3501–3508. http://dx.doi.org/10.1128/JCM.00834-12. 30. Sandiford JA, Higgins GA, Blair W. 1982. Remote salmonellosis: surgical masquerader. Am. Surg. 48:54 –58. 31. Bouvresse S, Chiras J, Bricaire F, Bossi P. 2006. Pott’s disease occurring after percutaneous vertebroplasty: an unusual illustration of the principle of locus minoris resistentiae. J. Infect. 53:e251–253. http://dx.doi.org/10 .1016/j.jinf.2006.02.014. 32. Chol C, Blanc PL, Forel C. 2008. Yersinia enterocolitica infection of a prosthetic knee joint. Med. Mal. Infect. 38:403– 405. (In French.) http://dx .doi.org/10.1016/j.medmal.2008.03.008. 33. Iglesias L, Garcia-Arenzana JM, Valiente A, Gomariz M, Perez-Trallero E. 2002. Yersinia enterocolitica O:3 infection of a prosthetic knee joint related to recurrent hemarthrosis. Scand. J. Infect. Dis. 34:132–133. http: //dx.doi.org/10.1080/00365540110080278. 34. Oni JA, Kangesu T. 1991. Yersinia enterocolitica infection of a prosthetic knee joint. Br. J. Clin. Pract. 45:225. 35. Musante DB, Ogden WS. 2004. Salmonella infection in joint arthroplasty. Orthopedics 27:770 –772. 36. Ranganath S, Midturi JK. 2013. Unusual case of prosthetic shoulder joint infection due to Clostridium difficile. Am. J. Med. Sci. 346:422– 423. http: //dx.doi.org/10.1097/MAJ.0b013e3182987d05. 37. Curtis L, Lipp MJ. 2013. Clostridium difficile infection of a prosthetic knee joint requiring amputation. Surg. Infect. (Larchmt.) 14:163–164. http: //dx.doi.org/10.1089/sur.2012.098. 38. McCarthy J, Stingemore N. 1999. Clostridium difficile infection of a prosthetic joint presenting 12 months after antibiotic-associated diarrhoea. J. Infect. 39:94 –96. http://dx.doi.org/10.1016/S0163-4453(99)90110-X. 39. Pron B, Merckx J, Touzet P, Ferroni A, Poyart C, Berche P, Gaillard JL. 1995. Chronic septic arthritis and osteomyelitis in a prosthetic knee joint due to Clostridium difficile. Eur. J. Clin. Microbiol. Infect. Dis. 14:599 – 601. http://dx.doi.org/10.1007/BF01690732. 40. Allos BM. 2013. Clinical manifestations, diagnosis, and treatment of Campylobacter infection. UpToDate. 41. Allos BM. 2010. Campylobacter jejuni and related species, p 2793–2802. In Mandell GL, Bennett JC, Dolin R (ed), Mandell, Douglas, and Bennett’s principles and practice of infectious disease, 7th ed, vol 2. Elsevier, Philadelphia, PA. 42. Maki DG. 2006. Don’t eat the spinach— controlling foodborne infectious disease. N. Engl. J. Med. 355:1952–1955. http://dx.doi.org/10.1056/NEJM p068225.

Journal of Clinical Microbiology

Downloaded from http://jcm.asm.org/ on August 12, 2014 by UNIVERSITY OF DAYTON LIBRARIES

7.

National Antimicrobial Resistance Monitoring System, Atlanta, GA. http: //www.cdc.gov/narms/pdf/2011-annual-report-narms-508c.pdf. Accessed 27 November 2013. Kurtz S, Ong K, Lau E, Mowat F, Halpern M. 2007. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J. Bone Joint Surg. Am. 89:780 –785. http://dx.doi.org/10 .2106/JBJS.F.00222. Centers for Disease Control and Prevention. 2013. Trends in Foodborne Illness in the United States, 2012. http://www.cdc.gov/features/dsfoodnet 2012/. Accessed 21 Nov 2013. Marculescu CE, Berbari EF, Cockerill FR, III, Osmon DR. 2006. Unusual aerobic and anaerobic bacteria associated with prosthetic joint infections. Clin. Orthop. Relat. Res. 451:55– 63. http://dx.doi.org/10.1097 /01.blo.0000229317.43631.81. Marculescu CE, Berbari EF, Cockerill FR, III, Osmon DR. 2006. Fungi, mycobacteria, zoonotic and other organisms in prosthetic joint infection. Clin. Orthop. Relat. Res. 451:64 –72. http://dx.doi.org/10.1097/01.blo .0000229337.21653.f2. Prendki V, Marmor S, Zeller V, Lhotellier L, Megraud F, Desplaces N. 2013. Campylobacter infection after prosthetic joint surgery. Scand. J. Infect. Dis. 45:706 –710. http://dx.doi.org/10.3109/00365548.2013.800225. David J, Nasser RM, Goldberg JW, Reed KD, Earll MD. 2005. Bilateral prosthetic knee infection by Campylobacter fetus. J. Arthroplasty 20:401– 405. http://dx.doi.org/10.1016/j.arth.2004.09.030. Yao JD, Ng HM, Campbell I. 1993. Prosthetic hip joint infection due to Campylobacter fetus. J. Clin. Microbiol. 31:3323–3324. Bates CJ, Clarke TC, Spencer RC. 1994. Prosthetic hip joint infection due to Campylobacter fetus. J. Clin. Microbiol. 32:2037. Chambers ST, Morpeth SC, Laird HM. 2005. Campylobacter fetus prosthetic hip joint infection: successful management with device retention and review. J. Infect. 50:258 –261. http://dx.doi.org/10.1016/j.jinf.2004.03 .017. Joly P, Boissonnas A, Fournier R, Khalifa P, Vedel G, Cremer GA, Languepin A, Kerboull M, Laroche C. 1986. Septic arthritis caused by Campylobacter fetus. Rev. Rhum. Mal. Osteoartic. 53:223–226. (In French.) Meyer A, Theulin A, Chatelus E, Argemi X, Sordet C, Javier RM, Hansmann Y, Sibilia J, Gottenberg JE. 2012. Campylobacter fetus infection in three rheumatoid arthritis patients treated with rituximab. Ann. Rheum. Dis. 71:1094 –1095. http://dx.doi.org/10.1136/annrheumdis-201 1-200719. Peterson MC, Farr RW, Castiglia M. 1993. Prosthetic hip infection and bacteremia due to Campylobacter jejuni in a patient with AIDS. Clin. Infect. Dis. 16:439 – 440. http://dx.doi.org/10.1093/clind/16.3.439. Sharp SE. 2009. Campylobacter coli prosthetic hip infection associated with ingestion of contaminated oysters. J. Clin. Microbiol. 47:3370 –3371. http://dx.doi.org/10.1128/JCM.00417-09. Almeida NJ, Murthy MH, Preheim LC. 2009. Prosthetic knee joint infection caused by Campylobacter gracilis. Infect. Dis. Clin. Pract. 17: 118 –119. http://dx.doi.org/10.1097/0b013e31817788b5. Werno AM, Klena JD, Shaw GM, Murdoch DR. 2002. Fatal case of Campylobacter lari prosthetic joint infection and bacteremia in an immunocompetent patient. J. Clin. Microbiol. 40:1053–1055. http://dx.doi.org /10.1128/JCM.40.3.1053-1055.2002. Issartel B, Pariset C, Roure C, Boibieux A, Peyramond D. 2002. Successful treatment of prosthetic knee infection due to Campylobacter upsaliensis. Eur. J. Clin. Microbiol. Infect. Dis. 21:234 –235. http://dx.doi.org /10.1007/s10096-001-0693-x. Garvin KL, Fitzgerald RH, Jr, Salvati EA, Brause BD, Nercessian OA, Wallrichs SL, Ilstrup DM. 1993. Reconstruction of the infected total hip and knee arthroplasty with gentamicin-impregnated Palacos bone cement. Instr. Course Lect. 42:293–302. Blaser MJ, Smith PF, Kohler PF. 1985. Susceptibility of Campylobacter isolates to the bactericidal activity of human serum. J. Infect. Dis. 151:227– 235. http://dx.doi.org/10.1093/infdis/151.2.227. Jerris RC, Fields PI, Nicholson MA. 2010. Fecal culture for Campylobacter and related organisms, section 3.8.2. In Garcia LS (ed), Clinical microbiology procedures handbook, 3rd ed, vol 1. ASM Press, Washington, DC.

Campylobacter prosthetic joint infection.

A 75-year-old man was diagnosed with probable Campylobacter jejuni prosthetic knee infection after a diarrheal illness. Joint aspirate and operative c...
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