Valensi et al. Cardiovasc Diabetol (2016) 15:104 DOI 10.1186/s12933-016-0415-4
Cardiovascular Diabetology Open Access
ORIGINAL INVESTIGATION
Atherogenic dyslipidemia and risk of silent coronary artery disease in asymptomatic patients with type 2 diabetes: a cross‑sectional study Paul Valensi1*, Antoine Avignon3,4, Ariane Sultan3,4, Bernard Chanu1, Minh Tuan Nguyen1 and Emmanuel Cosson1,2 Abstract Background: To investigate whether atherogenic dyslipidemia, a dyslipidemic profile combining elevated triglycerides and low high-density lipoprotein (HDL) cholesterol, is predictive of risk of silent myocardial ischemia (SMI) or angiographic coronary artery disease (CAD) in asymptomatic patients with type 2 diabetes. Methods: Cohort study in 1080 asymptomatic patients with type 2 diabetes with a normal resting electrocardiogram, at least one additional cardiovascular risk factor and low density lipoprotein (LDL) cholesterol 30 mg/day on at least two measurements and/or estimated glomerular filtration rate