BritishJoumal of Haematology, 1979, 41,19-24.
Association of IgA Multiple Myeloma with Preexisting Disease A. I. SCHAFER* A N D J. €3. MILLER
Department of Medicine] The University of Chicago Pritzker School of Medicine, and The Franklin McLean Memorial Research Institute (operated by The University of Chicagofor the U S . Department of Energy, under Contract No. EY-76-C-o2-0069), Chicago, Illinois, U.S.A. (Received 25January 1978; acceptedfor publication 7June 1978) SUMMARY. A retrospective analysis of 1 5 3 patients with multi.ple myeloma was performed for evaluation of the possible significance of pre-existing disease. 37% of the group had no significant antecedent disorder. The most common prior illnesses were peptic ulcer disease and gallbladder disease. O f 12 patients in the group who had prior biliary tract disease and for whom immunoelectrophoretic studies were available, eight (66.7%) had IgA paraproteins. This figure is statistically higher (P
Association of IgA Multiple Myeloma with Preexisting Disease A. I. SCHAFER* A N D J. €3. MILLER
Department of Medicine] The University of Chicago Pritzker School of Medicine, and The Franklin McLean Memorial Research Institute (operated by The University of Chicagofor the U S . Department of Energy, under Contract No. EY-76-C-o2-0069), Chicago, Illinois, U.S.A. (Received 25January 1978; acceptedfor publication 7June 1978) SUMMARY. A retrospective analysis of 1 5 3 patients with multi.ple myeloma was performed for evaluation of the possible significance of pre-existing disease. 37% of the group had no significant antecedent disorder. The most common prior illnesses were peptic ulcer disease and gallbladder disease. O f 12 patients in the group who had prior biliary tract disease and for whom immunoelectrophoretic studies were available, eight (66.7%) had IgA paraproteins. This figure is statistically higher (P
