Journal of Parenteral and Enteral Nutrition http://pen.sagepub.com/
Association Between Serum 25(OH)D Level and Nonspecific Musculoskeletal Pain in Acute Rehabilitation Unit Patients Debbie L. Matossian-Motley, Diane A. Drake, John S. Samimi, Carlos A. Camargo, Jr. and Sadeq A. Quraishi JPEN J Parenter Enteral Nutr published online 14 October 2014 DOI: 10.1177/0148607114555909 The online version of this article can be found at: http://pen.sagepub.com/content/early/2014/10/14/0148607114555909
Published by: http://www.sagepublications.com
On behalf of:
The American Society for Parenteral & Enteral Nutrition
Additional services and information for Journal of Parenteral and Enteral Nutrition can be found at: Email Alerts: http://pen.sagepub.com/cgi/alerts Subscriptions: http://pen.sagepub.com/subscriptions Reprints: http://www.sagepub.com/journalsReprints.nav Permissions: http://www.sagepub.com/journalsPermissions.nav
>> OnlineFirst Version of Record - Oct 14, 2014 What is This?
Downloaded from pen.sagepub.com at UNIV OF UTAH SALT LAKE CITY on October 16, 2014
555909
research-article2014
PENXXX10.1177/0148607114555909Journal of Parenteral and Enteral NutritionMatossian-Motley et al
Original Communication
Association Between Serum 25(OH)D Level and Nonspecific Musculoskeletal Pain in Acute Rehabilitation Unit Patients Debbie L. Matossian-Motley, RD, MPH, CNSC1; Diane A. Drake, RN, PhD2; John S. Samimi, PharmD3; Carlos A. Camargo Jr., MD, DrPH4,5,6; and Sadeq A. Quraishi, MD, MHA, MMSc7,8
Journal of Parenteral and Enteral Nutrition Volume XX Number X Month 201X 1–7 © 2014 American Society for Parenteral and Enteral Nutrition DOI: 10.1177/0148607114555909 jpen.sagepub.com hosted at online.sagepub.com
Abstract Objective: Nonspecific musculoskeletal pain can be difficult to manage in acute rehabilitation unit (ARU) patients. We investigated whether vitamin D status is a potential modifiable risk factor for nonspecific musculoskeletal pain in ARU patients. Materials and Methods: This cross-sectional study focused on 414 adults from an inpatient ARU in Mission Viejo, California, between July 2011 and June 2012. On ARU admission, all patients had serum 25-hydroxyvitamin D (25(OH)D) levels measured and were assessed for nonspecific musculoskeletal pain. We performed multivariable logistic regression to test the association of serum 25(OH)D level with nonspecific musculoskeletal pain while adjusting for clinically relevant covariates. Results: Among these 414 patients, mean (SD) 25(OH)D level was 29 (12) ng/mL, and 30% had nonspecific musculoskeletal pain. After adjustment for age, sex, race, body mass index, Functional Independence Measure score, Deyo-Charlson Comorbidity Index, fractures, steroid use, history of osteoporosis/osteomalacia, and patient type (orthopedic, cardiac, neurological, spinal cord injury, or traumatic brain injury), serum 25(OH)D level was inversely associated with nonspecific musculoskeletal pain (odds ratio [OR] per 10 ng/mL, 0.67; 95% confidence interval [CI], 0.48–0.82). When 25(OH)D level was dichotomized, patients with levels
Association Between Serum 25(OH)D Level and Nonspecific Musculoskeletal Pain in Acute Rehabilitation Unit Patients Debbie L. Matossian-Motley, Diane A. Drake, John S. Samimi, Carlos A. Camargo, Jr. and Sadeq A. Quraishi JPEN J Parenter Enteral Nutr published online 14 October 2014 DOI: 10.1177/0148607114555909 The online version of this article can be found at: http://pen.sagepub.com/content/early/2014/10/14/0148607114555909
Published by: http://www.sagepublications.com
On behalf of:
The American Society for Parenteral & Enteral Nutrition
Additional services and information for Journal of Parenteral and Enteral Nutrition can be found at: Email Alerts: http://pen.sagepub.com/cgi/alerts Subscriptions: http://pen.sagepub.com/subscriptions Reprints: http://www.sagepub.com/journalsReprints.nav Permissions: http://www.sagepub.com/journalsPermissions.nav
>> OnlineFirst Version of Record - Oct 14, 2014 What is This?
Downloaded from pen.sagepub.com at UNIV OF UTAH SALT LAKE CITY on October 16, 2014
555909
research-article2014
PENXXX10.1177/0148607114555909Journal of Parenteral and Enteral NutritionMatossian-Motley et al
Original Communication
Association Between Serum 25(OH)D Level and Nonspecific Musculoskeletal Pain in Acute Rehabilitation Unit Patients Debbie L. Matossian-Motley, RD, MPH, CNSC1; Diane A. Drake, RN, PhD2; John S. Samimi, PharmD3; Carlos A. Camargo Jr., MD, DrPH4,5,6; and Sadeq A. Quraishi, MD, MHA, MMSc7,8
Journal of Parenteral and Enteral Nutrition Volume XX Number X Month 201X 1–7 © 2014 American Society for Parenteral and Enteral Nutrition DOI: 10.1177/0148607114555909 jpen.sagepub.com hosted at online.sagepub.com
Abstract Objective: Nonspecific musculoskeletal pain can be difficult to manage in acute rehabilitation unit (ARU) patients. We investigated whether vitamin D status is a potential modifiable risk factor for nonspecific musculoskeletal pain in ARU patients. Materials and Methods: This cross-sectional study focused on 414 adults from an inpatient ARU in Mission Viejo, California, between July 2011 and June 2012. On ARU admission, all patients had serum 25-hydroxyvitamin D (25(OH)D) levels measured and were assessed for nonspecific musculoskeletal pain. We performed multivariable logistic regression to test the association of serum 25(OH)D level with nonspecific musculoskeletal pain while adjusting for clinically relevant covariates. Results: Among these 414 patients, mean (SD) 25(OH)D level was 29 (12) ng/mL, and 30% had nonspecific musculoskeletal pain. After adjustment for age, sex, race, body mass index, Functional Independence Measure score, Deyo-Charlson Comorbidity Index, fractures, steroid use, history of osteoporosis/osteomalacia, and patient type (orthopedic, cardiac, neurological, spinal cord injury, or traumatic brain injury), serum 25(OH)D level was inversely associated with nonspecific musculoskeletal pain (odds ratio [OR] per 10 ng/mL, 0.67; 95% confidence interval [CI], 0.48–0.82). When 25(OH)D level was dichotomized, patients with levels
