Original Article Association Between Perioperative Dexmedetomidine and Arrhythmias After Surgery for Congenital Heart Disease Jacqueline M. Shuplock, MD; Andrew H. Smith, MD, MSCI, MMHC; Jill Owen, RN, BSN; Sara L. Van Driest, MD, PhD; Matt Marshall, PharmD; Benjamin Saville, PhD; Meng Xu, MS; Andrew E. Radbill, MD; Frank A. Fish, MD; Prince J. Kannankeril, MD, MSCI Background—Dexmedetomidine is commonly used after congenital heart surgery and may be associated with a decreased incidence of postoperative tachyarrhythmias. Using a large cohort of patients undergoing congenital heart surgery, we examined for an association between dexmedetomidine use in the immediate postoperative period and subsequent arrhythmia development. Methods and Results—A total of 1593 surgical procedures for congenital heart disease were performed. Dexmedetomidine was administered in the immediate postoperative period after 468 (29%) surgical procedures. When compared with 1125 controls, the group receiving dexmedetomidine demonstrated significantly fewer tachyarrhythmias (29% versus 38%; P

Association between perioperative dexmedetomidine and arrhythmias after surgery for congenital heart disease.

Dexmedetomidine is commonly used after congenital heart surgery and may be associated with a decreased incidence of postoperative tachyarrhythmias. Us...
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