Downloaded from http://drc.bmj.com/ on September 11, 2017 - Published by group.bmj.com
Open Access
Research
Association between liver enzymes and incident type 2 diabetes in Singapore Chinese men and women Ye-Li Wang,1 Woon-Puay Koh,1,2 Jian-Min Yuan,3,4 An Pan5 To cite: Wang Y-L, Koh W-P, Yuan J-M, et al. Association between liver enzymes and incident type 2 diabetes in Singapore Chinese men and women. BMJ Open Diabetes Research and Care 2016;4: e000296. doi:10.1136/ bmjdrc-2016-000296
ABSTRACT Aims: To assess the association between liver
Received 8 July 2016 Revised 23 August 2016 Accepted 30 August 2016
enzymes and the risk of type 2 diabetes (T2D) in a Chinese population. Methods: A nested case–control study comprising 571 T2D cases and 571 matched controls was conducted within the Singapore Chinese Health Study. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) were quantified in baseline plasma collected from them, while γglutamyltransferase (GGT) was assayed among 255 T2D cases with baseline hemoglobin A1c
Open Access
Research
Association between liver enzymes and incident type 2 diabetes in Singapore Chinese men and women Ye-Li Wang,1 Woon-Puay Koh,1,2 Jian-Min Yuan,3,4 An Pan5 To cite: Wang Y-L, Koh W-P, Yuan J-M, et al. Association between liver enzymes and incident type 2 diabetes in Singapore Chinese men and women. BMJ Open Diabetes Research and Care 2016;4: e000296. doi:10.1136/ bmjdrc-2016-000296
ABSTRACT Aims: To assess the association between liver
Received 8 July 2016 Revised 23 August 2016 Accepted 30 August 2016
enzymes and the risk of type 2 diabetes (T2D) in a Chinese population. Methods: A nested case–control study comprising 571 T2D cases and 571 matched controls was conducted within the Singapore Chinese Health Study. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) were quantified in baseline plasma collected from them, while γglutamyltransferase (GGT) was assayed among 255 T2D cases with baseline hemoglobin A1c
