J Pediatr Endocr Met 2015; 28(5-6): 579–587
Fernanda Mussi Gazolla*, Maria Alice Neves Bordallo, Isabel Rey Madeira, Cecilia Noronha de Miranda Carvalho, Alexandra Maria Vieira Monteiro, Nádia Cristina Pinheiro Rodrigues, Marcos Antonio Borges, Paulo Ferrez Collett-Solberg, Bruna Moreira Muniz, Cecilia Lacroix de Oliveira, Suellen Martins Pinheiro and Rebeca Mathias de Queiroz Ribeiro
Association between cardiovascular risk factors and carotid intima-media thickness in prepubertal Brazilian children Abstract Background: Early exposure to cardiovascular risk factors creates a chronic inflammatory state that could damage the endothelium followed by thickening of the carotid intima-media. Objective: To investigate the association of cardiovascular risk factors and thickening of the carotid intima. Subjects/Methods: Media in prepubertal children. In this cross-sectional study, carotid intima-media thickness (cIMT) and cardiovascular risk factors were assessed in 129 prepubertal children aged from 5 to 10 year. Association was assessed by simple and multivariate logistic regression analyses.
*Corresponding author: Fernanda Mussi Gazolla, MD, Endocrinologist from the Unidade Docente Assistencial (UDA) de Endocrinologia e Metabologia, Hospital Universitário Pedro Ernesto (Pedro Ernesto Hospital) (HUPE), Universidade do Estado do Rio de Janeiro (State University of Rio de Janeiro) (UERJ) Rua Hélio Maurício, 103, Barra da Tijuca. Rio de Janeiro. Rio de Janeiro, Brasil, CEP: 22631-300, Phone: +55-21-33262107, +55-21-999879595, Fax: +55-21-33262107, E-mail: [email protected] Maria Alice Neves Bordallo: Associate Professor of Endocrinology, Faculdade de Ciências Médicas (Faculty of Medical Science) (FCM), UERJ Isabel Rey Madeira: Adjunct Professor of Pediatrics, FCM, UERJ Cecilia Noronha de Miranda Carvalho: Associate Professor of Nutrition, Instituto de Nutrição (Institute of Nutrition), UERJ Alexandra Maria Vieira Monteiro: Associate Professor of Radiology, FCM, UERJ Nádia Cristina Pinheiro Rodrigues: Adjunct Professor of Technology of Information and Health Education, FCM, UERJ Marcos Antonio Borges: Biologist from the UDA de Endocrinologia e Metabologia, HUPE, UERJ Paulo Ferrez Collett-Solberg: Adjunct Professor of Pediatric Endocrinology, FCM, UERJ Bruna Moreira Muniz and Suellen Martins Pinheiro: Resident in Nutrition from HUPE, UERJ Cecilia Lacroix de Oliveira: Adjunct Professor of Nutrition, Institute of Nutrition, UERJ Rebeca Mathias de Queiroz Ribeiro: Graduate Student of Medicine, FCM, UERJ
Results: In simple logistic regression analyses, body mass index (BMI) z-score, waist circumference, and systolic blood pressure (SBP) were positively associated with increased left, right, and average cIMT, whereas diastolic blood pressure was positively associated only with increased left and average cIMT (p
Fernanda Mussi Gazolla*, Maria Alice Neves Bordallo, Isabel Rey Madeira, Cecilia Noronha de Miranda Carvalho, Alexandra Maria Vieira Monteiro, Nádia Cristina Pinheiro Rodrigues, Marcos Antonio Borges, Paulo Ferrez Collett-Solberg, Bruna Moreira Muniz, Cecilia Lacroix de Oliveira, Suellen Martins Pinheiro and Rebeca Mathias de Queiroz Ribeiro
Association between cardiovascular risk factors and carotid intima-media thickness in prepubertal Brazilian children Abstract Background: Early exposure to cardiovascular risk factors creates a chronic inflammatory state that could damage the endothelium followed by thickening of the carotid intima-media. Objective: To investigate the association of cardiovascular risk factors and thickening of the carotid intima. Subjects/Methods: Media in prepubertal children. In this cross-sectional study, carotid intima-media thickness (cIMT) and cardiovascular risk factors were assessed in 129 prepubertal children aged from 5 to 10 year. Association was assessed by simple and multivariate logistic regression analyses.
*Corresponding author: Fernanda Mussi Gazolla, MD, Endocrinologist from the Unidade Docente Assistencial (UDA) de Endocrinologia e Metabologia, Hospital Universitário Pedro Ernesto (Pedro Ernesto Hospital) (HUPE), Universidade do Estado do Rio de Janeiro (State University of Rio de Janeiro) (UERJ) Rua Hélio Maurício, 103, Barra da Tijuca. Rio de Janeiro. Rio de Janeiro, Brasil, CEP: 22631-300, Phone: +55-21-33262107, +55-21-999879595, Fax: +55-21-33262107, E-mail: [email protected] Maria Alice Neves Bordallo: Associate Professor of Endocrinology, Faculdade de Ciências Médicas (Faculty of Medical Science) (FCM), UERJ Isabel Rey Madeira: Adjunct Professor of Pediatrics, FCM, UERJ Cecilia Noronha de Miranda Carvalho: Associate Professor of Nutrition, Instituto de Nutrição (Institute of Nutrition), UERJ Alexandra Maria Vieira Monteiro: Associate Professor of Radiology, FCM, UERJ Nádia Cristina Pinheiro Rodrigues: Adjunct Professor of Technology of Information and Health Education, FCM, UERJ Marcos Antonio Borges: Biologist from the UDA de Endocrinologia e Metabologia, HUPE, UERJ Paulo Ferrez Collett-Solberg: Adjunct Professor of Pediatric Endocrinology, FCM, UERJ Bruna Moreira Muniz and Suellen Martins Pinheiro: Resident in Nutrition from HUPE, UERJ Cecilia Lacroix de Oliveira: Adjunct Professor of Nutrition, Institute of Nutrition, UERJ Rebeca Mathias de Queiroz Ribeiro: Graduate Student of Medicine, FCM, UERJ
Results: In simple logistic regression analyses, body mass index (BMI) z-score, waist circumference, and systolic blood pressure (SBP) were positively associated with increased left, right, and average cIMT, whereas diastolic blood pressure was positively associated only with increased left and average cIMT (p
![[Thickness of carotid intima-media and cardiovascular risk factors].](/assets/img/hold.png)
