Eur Radiol DOI 10.1007/s00330-015-3841-x
MAGNETIC RESONANCE
Assessment of renal allograft function early after transplantation with isotropic resolution diffusion tensor imaging Wen-jun Fan 1,2 & Tao Ren 1 & Qiong Li 1 & Pan-li Zuo 4 & Miao-miao Long 1 & Chun-bai Mo 3 & Li-hua Chen 1 & Li-xiang Huang 1 & Wen Shen 1
Received: 3 December 2014 / Revised: 2 May 2015 / Accepted: 11 May 2015 # European Society of Radiology 2015
Abstract Objectives To investigate the value of diffusion tensor imaging (DTI) and tractography in renal allografts at the early stage after kidney transplantation. Methods This study was approved by the institutional ethical review committee, and written informed consent was obtained. A total of 54 renal allograft recipients 2–3 weeks after transplantation and 26 age-matched healthy volunteers underwent renal DTI with a 3.0-T magnetic resonance imaging (MRI) system. Recipients were divided into three groups according to the estimated glomerular filtration rate (eGFR). Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) of the cortex and medulla were measured and compared among the groups. Whole-kidney tractography was performed. Correlation of eGFR with diffusion parameters was evaluated. Results In allografts with stable function, the medullary ADC was higher and the cortical FA was lower (p
MAGNETIC RESONANCE
Assessment of renal allograft function early after transplantation with isotropic resolution diffusion tensor imaging Wen-jun Fan 1,2 & Tao Ren 1 & Qiong Li 1 & Pan-li Zuo 4 & Miao-miao Long 1 & Chun-bai Mo 3 & Li-hua Chen 1 & Li-xiang Huang 1 & Wen Shen 1
Received: 3 December 2014 / Revised: 2 May 2015 / Accepted: 11 May 2015 # European Society of Radiology 2015
Abstract Objectives To investigate the value of diffusion tensor imaging (DTI) and tractography in renal allografts at the early stage after kidney transplantation. Methods This study was approved by the institutional ethical review committee, and written informed consent was obtained. A total of 54 renal allograft recipients 2–3 weeks after transplantation and 26 age-matched healthy volunteers underwent renal DTI with a 3.0-T magnetic resonance imaging (MRI) system. Recipients were divided into three groups according to the estimated glomerular filtration rate (eGFR). Apparent diffusion coefficient (ADC) and fractional anisotropy (FA) of the cortex and medulla were measured and compared among the groups. Whole-kidney tractography was performed. Correlation of eGFR with diffusion parameters was evaluated. Results In allografts with stable function, the medullary ADC was higher and the cortical FA was lower (p
