CLINICAL RESEARCH e-ISSN 1643-3750 © Med Sci Monit, 2017; 23: 1340-1346 DOI: 10.12659/MSM.900212

Assessment of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Atopic Dermatitis Patients

Received: 2016.06.22 Accepted: 2016.08.10 Published: 2017.03.17

Authors’ Contribution: Study Design  A Data Collection  B Statistical Analysis  C Data Interpretation  D Manuscript Preparation  E Literature Search  F Funds Collection  G

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Ying Jiang Wencong Ma

1 Department of Dermatology, 1st Hospital of Jilin University, Changchun, Jilin, P.R. China 2 Department of Surgery, 1st Hospital of Jilin University, Changchun, Jilin, P.R. China

Wencong Ma, e-mail: [email protected] Departmental sources

To develop new strategies for identifying atopic dermatitis patients, a better understanding of the signs for chronic inflammatory status is needed. This study was designed to investigate whether neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are related to the severity of atopic dermatitis (AD) assessed by the Scoring Atopic Dermatitis (SCORAD) index. A retrospective study involving 80 AD patients and 45 healthy control subjects was performed. NLR, PLR, and the number of peripheral blood eosinophils were compared between AD patients and healthy controls, and correlations between these indexes and clinical characteristics were analyzed. NLR, PLR, and eosinophils in AD patients were all significantly higher than in healthy individuals. Among AD patients, NLR (p