Environ Sci Pollut Res DOI 10.1007/s11356-014-3128-9

RESEARCH ARTICLE

Assessment of genotoxic effects of lead in occupationally exposed workers Srinivas Chinde & Monika Kumari & Kanapuram Rudrama Devi & Upadhyayula Suryanarayana Murty & Mohammed Fazlur Rahman & Srinivas Indu Kumari & Mohammed Mahboob & Paramjit Grover

Received: 11 April 2014 / Accepted: 28 May 2014 # Springer-Verlag Berlin Heidelberg 2014

Abstract The genotoxicological effects in 200 lead acid storage battery recycling and manufacturing industry workers in Hyderabad along with matched 200 controls were studied. The genetic damage was determined by comet, micronucleus (MN), and chromosomal aberration (CA) test in peripheral blood lymphocytes (PBL). The MN test was also carried out in buccal epithelial cells (BECs). Pb in ambient air, blood Pb (B-Pb) concentrations, and hematological parameters were measured. The superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), glutathione peroxidase (GPx), and malondialdehyde (MDA) formed were also studied. The results of the present study showed that there was a statistically significant (P

Assessment of genotoxic effects of lead in occupationally exposed workers.

The genotoxicological effects in 200 lead acid storage battery recycling and manufacturing industry workers in Hyderabad along with matched 200 contro...
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