NIH Public Access Author Manuscript Pac Symp Biocomput. Author manuscript; available in PMC 2015 January 01.
NIH-PA Author Manuscript
Published in final edited form as: Pac Symp Biocomput. 2014 ; : 412–416.
APPLICATIONS OF BIOINFORMATICS TO NON-CODING RNAS IN THE ERA OF NEXT-GENERATION SEQUENCING CHAO CHENG, Department of Genetics, Institute for Quantitative Biomedical Sciences, Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College Hanover, NH 03755, USA JASON MOORE, and Department of Genetics, Institute for Quantitative Biomedical Sciences, Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College Hanover, NH 03755, USA CASEY GREENE Department of Genetics, Institute for Quantitative Biomedical Sciences, Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College Hanover, NH 03755, USA
NIH-PA Author Manuscript
CHAO CHENG: [email protected]; JASON MOORE: [email protected]; CASEY GREENE: [email protected]
Abstract The human genome encodes a large number of non-coding RNAs, which employ a new and crucial layer of biological regulation in addition to proteins. Technical advancement in recent years, particularly, the wide application of next generation sequencing analysis, provide an unprecedented opportunity to identify new non-coding RNAs and investigate their functions and regulatory mechanisms. The aim of this workshop is to bring together experimental and computational biologist to exchange ideas on non-coding RNA studies.
1. Background
NIH-PA Author Manuscript
Non-coding RNAs (ncRNAs) are RNA molecules encoded by genes in the genome that are transcribed and functional but not translated into proteins. Recent studies have shown that more than 90% human genome is transcribed but coding sequences occupy only a small fraction of the genome (
NIH-PA Author Manuscript
Published in final edited form as: Pac Symp Biocomput. 2014 ; : 412–416.
APPLICATIONS OF BIOINFORMATICS TO NON-CODING RNAS IN THE ERA OF NEXT-GENERATION SEQUENCING CHAO CHENG, Department of Genetics, Institute for Quantitative Biomedical Sciences, Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College Hanover, NH 03755, USA JASON MOORE, and Department of Genetics, Institute for Quantitative Biomedical Sciences, Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College Hanover, NH 03755, USA CASEY GREENE Department of Genetics, Institute for Quantitative Biomedical Sciences, Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College Hanover, NH 03755, USA
NIH-PA Author Manuscript
CHAO CHENG: [email protected]; JASON MOORE: [email protected]; CASEY GREENE: [email protected]
Abstract The human genome encodes a large number of non-coding RNAs, which employ a new and crucial layer of biological regulation in addition to proteins. Technical advancement in recent years, particularly, the wide application of next generation sequencing analysis, provide an unprecedented opportunity to identify new non-coding RNAs and investigate their functions and regulatory mechanisms. The aim of this workshop is to bring together experimental and computational biologist to exchange ideas on non-coding RNA studies.
1. Background
NIH-PA Author Manuscript
Non-coding RNAs (ncRNAs) are RNA molecules encoded by genes in the genome that are transcribed and functional but not translated into proteins. Recent studies have shown that more than 90% human genome is transcribed but coding sequences occupy only a small fraction of the genome (
