Antitumor activity of fluoropyrimidines and thymidylate synthetase inhibition.

Multivariate analysis and quantitative structure-activity relationships. Inhibition of dihydrofolate reductase and thymidylate synthetase by quinazolines.

Assay of intracellular thymidylate synthetase activity and inhibition by 5-fluoro-2'-deoxyuridine in lymphocytes.

Interferon alpha-2a shows antitumor activity in combination with 5-fluorouracil against human colon carcinoma xenografts: a study in reference to thymidylate synthetase activity inhibition.

Antitumor activity of two novel low immunosuppressive fluoropyrimidines UK-21 and UK-25.

Synthesis of 5-selenium-substituted uracil derivatives. Inhibition of thymidylate synthetase by 5-hydroseleno-2'-deoxyuridylate.

Inhibition of thymidylate synthetase of Walker carcinoma by chlorambucil. A possible mechanism of action.

Cytotoxicity of 5-nitro-2'-deoxyuridine by in vivo inhibition of thymidylate synthetase.

Human thymidylate synthetase--III. Effects of methotrexate and folate analogs.

Activities of thymidylate synthetase and thymidine kinase in gastric cancer.

Bacteriophage T4 virion baseplate thymidylate synthetase and dihydrofolate reductase.

Increased thymidylate synthetase activity in 5-fluorodeoxyuridine-resistant Novikoff hepatoma cells.

19F NMR of the 5-fluorodeoxyuridylate-thymidylate synthetase binary complex.

Characteristics of NADPH-dependent thymidylate synthetase purified from Streptomyces aureofaciens.

Thymidylate synthetase purified to homogeneity from human leukemic cells.

Inhibition of cancer-associated mutant isocitrate dehydrogenases: synthesis, structure-activity relationship, and selective antitumor activity.

Thymidylate synthetase. Catalysis of dehalogenation of 5-bromo- and 5-iodo-2'-deoxyuridylate.

Bacteriophage T4 baseplate components. III. Location and properties of the bacteriophage structural thymidylate synthetase.

Thymidine phosphorylase, thymidine kinase and thymidylate synthetase activities in cerebral hemispheres of developing chick embryos.

Thymidylate synthetase of in vitro chemically and virally transformed rat cells.

Increased activities of thymidylate synthetase and thymidine kinase in human thyroid tumors.

Dihydrofolate reductase and thymidylate synthetase activities in the liver of rabbit foetuses during the haemapoietic period.

Inhibition of thymidylate synthase by the diastereoisomers of leucovorin.

Synthesis of hydroxy- and amino-substituted benzohydroxamic acids: inhibition of ribonucleotide reductase and antitumor activity.

Irreversible inhibition of thymidylate synthase by pyridoxine (B6) analogues.

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Multivariate analysis and quantitative structure-activity relationships. Inhibition of dihydrofolate reductase and thymidylate synthetase by quinazolines.

Assay of intracellular thymidylate synthetase activity and inhibition by 5-fluoro-2'-deoxyuridine in lymphocytes.

Interferon alpha-2a shows antitumor activity in combination with 5-fluorouracil against human colon carcinoma xenografts: a study in reference to thymidylate synthetase activity inhibition.

Antitumor activity of two novel low immunosuppressive fluoropyrimidines UK-21 and UK-25.

Synthesis of 5-selenium-substituted uracil derivatives. Inhibition of thymidylate synthetase by 5-hydroseleno-2'-deoxyuridylate.

Inhibition of thymidylate synthetase of Walker carcinoma by chlorambucil. A possible mechanism of action.

Cytotoxicity of 5-nitro-2'-deoxyuridine by in vivo inhibition of thymidylate synthetase.

Human thymidylate synthetase--III. Effects of methotrexate and folate analogs.

Activities of thymidylate synthetase and thymidine kinase in gastric cancer.

Bacteriophage T4 virion baseplate thymidylate synthetase and dihydrofolate reductase.

Increased thymidylate synthetase activity in 5-fluorodeoxyuridine-resistant Novikoff hepatoma cells.

19F NMR of the 5-fluorodeoxyuridylate-thymidylate synthetase binary complex.

Characteristics of NADPH-dependent thymidylate synthetase purified from Streptomyces aureofaciens.

Thymidylate synthetase purified to homogeneity from human leukemic cells.

Inhibition of cancer-associated mutant isocitrate dehydrogenases: synthesis, structure-activity relationship, and selective antitumor activity.

Thymidylate synthetase. Catalysis of dehalogenation of 5-bromo- and 5-iodo-2'-deoxyuridylate.

Bacteriophage T4 baseplate components. III. Location and properties of the bacteriophage structural thymidylate synthetase.

Thymidine phosphorylase, thymidine kinase and thymidylate synthetase activities in cerebral hemispheres of developing chick embryos.

Thymidylate synthetase of in vitro chemically and virally transformed rat cells.

Increased activities of thymidylate synthetase and thymidine kinase in human thyroid tumors.

Dihydrofolate reductase and thymidylate synthetase activities in the liver of rabbit foetuses during the haemapoietic period.

Inhibition of thymidylate synthase by the diastereoisomers of leucovorin.

Synthesis of hydroxy- and amino-substituted benzohydroxamic acids: inhibition of ribonucleotide reductase and antitumor activity.

Irreversible inhibition of thymidylate synthase by pyridoxine (B6) analogues.

Antitumor activity of fluoropyrimidines and thymidylate synthetase inhibition.

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