AAC Accepted Manuscript Posted Online 16 February 2016 Antimicrob. Agents Chemother. doi:10.1128/AAC.02897-15 Copyright © 2016, American Society for Microbiology. All Rights Reserved.
1
Antibiotic Resistance among Urinary Isolates from Female Outpatients in the United
2
States in 2003 and 2012
3
Guillermo V. Sanchez 1, PA-C, MPH, Ahmed Babiker2, MBBS; Ronald N. Master3, MS,
4
Tony Luu4, PharmD, Anisha Mathur2, MD, Jose Bordon2, MD, PhD.
5
Author Affiliations:
6
1) Department of Emergency Medicine, Emory University School of Medicine, 1365 Clifton Rd Ne, Atlanta, GA 30322
7 8
2) Section of Infectious Disease, Providence Hospital, 1150 Varnum St NE, Washington, DC, United States.
9 10
3) Quest Diagnostics Nichols Institute, 14225 Newbrook Dr, Chantilly, VA, United States.
11 12
4) School of Pharmacy, University of Southern California, 1985 Zonal Ave, Los Angeles, United States.
13 14
Abstract word count:
145 (limit is 250)
15
Manuscript word count:
1515 (limit is 1500)
16
Keywords: Community, urinary tract infection, antibiotic resistance, guidelines, primary care,
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ciprofloxacin, sulfonamides, nitrofurantoin
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Running Title: Antibiotic Resistance in Outpatient UTIs
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Correspondence to:
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Jose Bordon, M.D., Ph.D., AAHIVS
21
Providence Hospital, Chief of the Section of Infectious Diseases
22
1150 Varnum St NE, Washington, DC 20017
23
Phone:
202-854-4052
24
Fax:
202-854-4832
25
E-mail:
[email protected]
26
Abstract
27
A retrospective analysis was performed using The Surveillance Network®, USA, to examine
28
the prevalence of antibiotic resistance among urine isolates from female U.S. outpatients in
29
2012, and assessed trends in antibiotic resistance comparing 2003 to 2012. The most common
30
pathogen identified in 2012 (N=285,325) was Escherichia coli (64.9% of isolates). In 2012,
31
E. coli resistance to nitrofurantoin was low (
1
Antibiotic Resistance among Urinary Isolates from Female Outpatients in the United
2
States in 2003 and 2012
3
Guillermo V. Sanchez 1, PA-C, MPH, Ahmed Babiker2, MBBS; Ronald N. Master3, MS,
4
Tony Luu4, PharmD, Anisha Mathur2, MD, Jose Bordon2, MD, PhD.
5
Author Affiliations:
6
1) Department of Emergency Medicine, Emory University School of Medicine, 1365 Clifton Rd Ne, Atlanta, GA 30322
7 8
2) Section of Infectious Disease, Providence Hospital, 1150 Varnum St NE, Washington, DC, United States.
9 10
3) Quest Diagnostics Nichols Institute, 14225 Newbrook Dr, Chantilly, VA, United States.
11 12
4) School of Pharmacy, University of Southern California, 1985 Zonal Ave, Los Angeles, United States.
13 14
Abstract word count:
145 (limit is 250)
15
Manuscript word count:
1515 (limit is 1500)
16
Keywords: Community, urinary tract infection, antibiotic resistance, guidelines, primary care,
17
ciprofloxacin, sulfonamides, nitrofurantoin
18
Running Title: Antibiotic Resistance in Outpatient UTIs
19
Correspondence to:
20
Jose Bordon, M.D., Ph.D., AAHIVS
21
Providence Hospital, Chief of the Section of Infectious Diseases
22
1150 Varnum St NE, Washington, DC 20017
23
Phone:
202-854-4052
24
Fax:
202-854-4832
25
E-mail:
[email protected]
26
Abstract
27
A retrospective analysis was performed using The Surveillance Network®, USA, to examine
28
the prevalence of antibiotic resistance among urine isolates from female U.S. outpatients in
29
2012, and assessed trends in antibiotic resistance comparing 2003 to 2012. The most common
30
pathogen identified in 2012 (N=285,325) was Escherichia coli (64.9% of isolates). In 2012,
31
E. coli resistance to nitrofurantoin was low (
