Official Journal of the American Neurological Association

Aims and Scope Annals of Clinical and Translational Neurology is a peer-reviewed journal for rapid dissemination of high-quality research related to all areas of neurology. The journal publishes original research and scholarly reviews focused on the mechanisms and treatments of diseases of the nervous system; high-impact topics in neurologic education; and other topics of interest to the clinical neuroscience community. All areas of clinical and basic neuroscience, including new technologies, cellular and molecular neurobiology, population sciences, and studies of behavior, addiction, and psychiatric diseases are of interest to the journal. Annals of Clinical and Translational Neurology is particularly interested in clinical trials and other large-scale studies that inform the practice of medicine. Trials reporting negative data will be considered. In addition to manuscripts from established investigators, Annals of Clinical and Translational Neurology will welcome scholarly work, points-of-view, and case studies from residents, fellows and medical students. Annals of Clinical and Translational Neurology publishes papers submitted directly to the journal and those referred from Annals of Neurology.

Open Access and Copyright All articles published by Annals of Clinical and Translational Neurology are fully open access: immediately freely available to read, download and share. All Annals of Clinical and Translational Neurology articles are published under a Creative Commons License. All Research Councils UK (RCUK) and Wellcome Trust funded authors will be directed to the Creative Commons Attribution license (CC BY) in accordance with funder mandates effective on 1 April 2013. All other authors (non-RCUK and Wellcome Trust authors) will use the Attribution-Non-Commercial-NoDerivs (CC BY NC ND). Copyright on any research article in a journal published by Annals of Clinical and Translational Neurology is retained by the author(s). Authors grant Wiley a license to publish the article and identify itself as the original publisher. Authors also grant any third party the right to use the article freely as long as its integrity is maintained and its original authors, citation details and publisher are identified. Further information about open access license and copyright can be found at http://www.wileyopenaccess.com/details/content/12f25db4c87/ Copyright-License.html.

Purchasing Print Reprints Print reprints of Wiley Open Access articles can be purchased from [email protected]

Disclaimer The Publisher, American Neurological Association and Editors cannot be held responsible for errors or any consequences arising from the use of information contained in this journal; the views and opinions expressed do not necessarily reflect those of the Publisher, American Neurological Association and Editors, neither does the publication of advertisements constitute any endorsements by the Publisher, American Neurological Association and Editors of the products advertised. Wiley Open Access articles posted to repositories or websites are without warranty from Wiley of any kind, either express or implied, including, but not limited to, warranties of merchantability, fitness for a particular purpose, or non-infringement. To the fullest extent permitted by law Wiley disclaims all liability for any loss or damage arising out of, or in connection with, the use of or inability to use the content.

Editor-in-Chief John Kessler, MD Northwestern University, Chicago Address correspondence to the Editorial Office: [email protected]

Associate Editors Flint Beal Cornell University Medical College New York

Anne Cross Washington University St. Louis

Andrew J. Cole MGH/Harvard Boston

Leon Epstein Northwestern University Chicago

Ahmet Hoke Johns Hopkins Baltimore

Steven Warach University of Texas Southwestern Dallas

Editorial Board Susan Bressman Mt. Sinai New York

David Holtzman Washington University St. Louis

Tanya Simuni Northwestern Chicago

Charlotte Sumner Johns Hopkins Baltimore

Sydney Cash MGH/Harvard Boston

Michael Racke Ohio State Columbus

Gordon Smith University of Utah Salt Lake City

Emmanuelle Waubant University of California San Francisco

Merit Cudkowicz MGH/Harvard Boston

Sean Savitz University of Texas Houston

Kevin Staley MGH/Harvard Boston

Annals of clinical and translational neurology.

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