HIPPOKRATIA 2013, 17, 4: 307-312

ORIGINAL ARTICLE

Anemia is independently associated with NT-proBNP levels in asymptomatic predialysis patients with chronic kidney disease Tirmenstajn-Jankovic B1, Dimkovic N2, Perunicic-Pekovic G3, Radojicic Z4, Bastac D5, Zikic S1, Zivanovic M1 Department of Nephrology and Hemodialysis, Medical Center Zajecar Clinical Department for Renal Disease, Zvezdara University Medical Center, Belgrade 3 Department of Nephrology, University Hospital Zemun-Belgrade 4 Institute for Statistics, Faculty of Organizational Sciences, University of Belgrade 5 Office of Internal Medicine «Dr Bastac», Zajecar Serbia 1 2

Abstract Background: Although anemia and renal dysfunction are related to increased natriuretic peptides levels in heart failure patients, less is known about this relationship in asymptomatic predialysis patients with chronic kidney disease (CKD). The aim of this study was to investigate relationship between hemoglobin (Hb) concentration, N-terminal proBNP (NTproBNP) levels and echocardiographic findings in these patients. Methods: The study included 61 patients with CKD stage IV-V (34 male, mean age 62.6 ± 13.6 years) and 22 age- and sex -matched healthy persons as control group. All participants underwent clinical, laboratory and echocardiographic examination, including Tissue Doppler Imaging and colour M-mode Doppler. Results: Patients with CKD had lower Hb levels (p

Anemia is independently associated with NT-proBNP levels in asymptomatic predialysis patients with chronic kidney disease.

Although anemia and renal dysfunction are related to increased natriuretic peptides levels in heart failure patients, less is known about this relatio...
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