ORIGINAL ARTICLE LUNG CANCER
Analysis of advanced lung cancer patients diagnosed following emergency admission Daichi Fujimoto1, Ryoko Shimizu1, Takeshi Morimoto2,3, Ryoji Kato1, Yuki Sato1, Mariko Kogo1, Jiro Ito1, Shunsuke Teraoka1, Takehiro Otoshi1, Kazuma Nagata1, Atsushi Nakagawa1, Kojiro Otsuka1, Nobuyuki Katakami1 and Keisuke Tomii1 Affiliations: 1 Dept of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan. 2 Clinical Research Center, Kobe City Medical Center General Hospital, Kobe, Japan. 3 Division of General Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan. Correspondence: Daichi Fujimoto, Dept of Respiratory Medicine, Kobe City Medical Center General Hospital, 2 MinatojimaMinamimachi, Chuo-ku, Kobe 650-0047, Japan. E-mail: [email protected]
ABSTRACT Data on prognosis and predictors of overall survival in advanced lung cancer patients diagnosed following emergency admission (DFEA) are currently lacking. We retrospectively analysed data from 771 patients with advanced nonsmall cell lung cancer between April 2004 and April 2012. Of the 771 patients, 103 (13%) were DFEA. DFEA was not an independent predictor of overall survival by multivariate Cox proportional hazard models, whereas good performance status (PS), epidermal growth factor receptor gene mutation, stage IIIB, adenocarcinoma and chemotherapy were independent predictors of overall survival (hazard ratio (95% CI) 0.36 (0.29–0.44), p
Analysis of advanced lung cancer patients diagnosed following emergency admission Daichi Fujimoto1, Ryoko Shimizu1, Takeshi Morimoto2,3, Ryoji Kato1, Yuki Sato1, Mariko Kogo1, Jiro Ito1, Shunsuke Teraoka1, Takehiro Otoshi1, Kazuma Nagata1, Atsushi Nakagawa1, Kojiro Otsuka1, Nobuyuki Katakami1 and Keisuke Tomii1 Affiliations: 1 Dept of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan. 2 Clinical Research Center, Kobe City Medical Center General Hospital, Kobe, Japan. 3 Division of General Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan. Correspondence: Daichi Fujimoto, Dept of Respiratory Medicine, Kobe City Medical Center General Hospital, 2 MinatojimaMinamimachi, Chuo-ku, Kobe 650-0047, Japan. E-mail: [email protected]
ABSTRACT Data on prognosis and predictors of overall survival in advanced lung cancer patients diagnosed following emergency admission (DFEA) are currently lacking. We retrospectively analysed data from 771 patients with advanced nonsmall cell lung cancer between April 2004 and April 2012. Of the 771 patients, 103 (13%) were DFEA. DFEA was not an independent predictor of overall survival by multivariate Cox proportional hazard models, whereas good performance status (PS), epidermal growth factor receptor gene mutation, stage IIIB, adenocarcinoma and chemotherapy were independent predictors of overall survival (hazard ratio (95% CI) 0.36 (0.29–0.44), p
