Antiviral Therapy 2015; 20:521–527 (doi: 10.3851/IMP2940)
Original article Anaemia is associated with monocyte activation in HIV-infected adults on antiretroviral therapy Hannah M Lipshultz1, Corrilynn O Hileman1,2, Sanjay Ahuja1,3, Nicholas T Funderburg4, Grace A McComsey1,3,5* Case Western Reserve University School of Medicine, Cleveland, OH, USA MetroHealth Medical Center, Department of Medicine, Cleveland, OH, USA 3 University Hospitals Case Medical Center, Department of Pediatrics, Cleveland, OH, USA 4 Ohio State University School of Health and Rehabilitation Sciences, Division of Medical Laboratory Science, Columbus, OH, USA 5 University Hospitals Case Medical Center, Department of Medicine, Cleveland, OH, USA 1 2
*Corresponding author e-mail: [email protected]
Background: Anaemia has been linked with mortality in HIV infection. The mechanism of anaemia in the era of contemporary antiretroviral therapy is not understood. The aim of this study was to describe the association between anaemia and markers of immune activation and inflammation in a cohort of HIV-infected adults on stable antiretroviral therapy. Methods: We performed a cross-sectional study of HIVinfected adults on antiretroviral therapy with HIV-1 RNA
Original article Anaemia is associated with monocyte activation in HIV-infected adults on antiretroviral therapy Hannah M Lipshultz1, Corrilynn O Hileman1,2, Sanjay Ahuja1,3, Nicholas T Funderburg4, Grace A McComsey1,3,5* Case Western Reserve University School of Medicine, Cleveland, OH, USA MetroHealth Medical Center, Department of Medicine, Cleveland, OH, USA 3 University Hospitals Case Medical Center, Department of Pediatrics, Cleveland, OH, USA 4 Ohio State University School of Health and Rehabilitation Sciences, Division of Medical Laboratory Science, Columbus, OH, USA 5 University Hospitals Case Medical Center, Department of Medicine, Cleveland, OH, USA 1 2
*Corresponding author e-mail: [email protected]
Background: Anaemia has been linked with mortality in HIV infection. The mechanism of anaemia in the era of contemporary antiretroviral therapy is not understood. The aim of this study was to describe the association between anaemia and markers of immune activation and inflammation in a cohort of HIV-infected adults on stable antiretroviral therapy. Methods: We performed a cross-sectional study of HIVinfected adults on antiretroviral therapy with HIV-1 RNA
