Tropical Medicine and International Health

doi:10.1111/tmi.12216

volume 19 no 1 pp 117–122 january 2014

Short Communication

Anaemia, iron deficiency and a common polymorphism of iron-regulation, TMPRSS6 rs855791, in Rwandan children Ina Danquah1, Jean-Bosco Gahutu2, Irene Zeile3, Andre Musemakweri2 and Frank P. Mockenhaupt3 1 Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany 2 Faculty of Medicine, Butare University Teaching Hospital, National University of Rwanda, Butare, Rwanda 3 Institute of Tropical Medicine and International Health, Charité – University Medicine Berlin, Berlin, Germany

Abstract

Anaemia in children living in sub-Saharan Africa is common, but its causes are diverse. In 545 children below 5 years of age from rural southern Rwanda, we assessed the role of iron deficiency (ID) and of the TMPRSS6 736(V) (rs855791) allele, known to reduce iron status and haemoglobin (Hb) levels, in anaemia and Hb concentrations. Anaemia (Hb

Anaemia, iron deficiency and a common polymorphism of iron-regulation, TMPRSS6 rs855791, in Rwandan children.

Anaemia in children living in sub-Saharan Africa is common, but its causes are diverse. In 545 children below 5 years of age from rural southern Rwand...
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