Articles in PresS. Am J Physiol Endocrinol Metab (November 25, 2014). doi:10.1152/ajpendo.00689.2013
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Anabolic Responses to Acute and Chronic Resistance Exercise Are Enhanced When
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Combined With Aquatic Treadmill Exercise
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Lambert, B.S. 1, Shimkus, K.L.2, Fluckey, J.D.2, Riechman, S.E.3, Greene, N.P.4, Cardin, J.M.2,
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Crouse, S.F.1
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Affiliations:
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1
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Station, TX 77843
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Applied Exercise Science Laboratory, Department of Health & Kinesiology, Texas A&M University, College
Muscle Biology Laboratory, Department of Health & Kinesiology, Texas A&M University, College Station, TX
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77843
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Station, TX 77843
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Arkansas, Fayetteville, AR 72701
Human Countermeasures Laboratory, Department of Health & Kinesiology, Texas A&M University, College
Human Performance Laboratory, Department of Health, Human Performance and Recreation, University of
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Running Title: ATM Running Enhances Adaptations to Resistance Training
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Author Contributions: BSL and SFC are responsible for conception of the study; BSL, NPG, JDF, SER, and SFC are
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responsible for the study design; BSL, NPG, JDF, and SER were involved in collection of the data; BSL analyzed
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all muscle samples with assistance from KLS and JMC; BSL prepared figures and drafted the manuscript; All co-
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authors revised and edited the manuscript; SFC approved the final manuscript.
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Corresponding Author:
Brad S. Lambert
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[email protected] 23
Department of Nutrition and Metabolism
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University of Texas Medical Branch
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301 University Blvd.
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Galveston, TX 77555
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Copyright © 2014 by the American Physiological Society.
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Abstract
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muscle growth when combined with resistance training (RT) compared to land-treadmill (LTM)
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running. Therefore, we examined acute and chronic physiological responses to RT, concurrent
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RT-LTM and concurrent RT-ATM. Forty-seven untrained volunteers (♂n=23, 37±11yr,
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29.6±4.6 kg·m2| ♀n=24, 38±12yr, 27.53±6.4 kg·m2) from the general population were tested for
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VO2max, body composition, and strength before and after training. All groups performed 12wks
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of RT (2·wk, 3 x 8-12 @ 60→~80%1RM). The RT-LTM & RT-ATM groups also performed
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12wks of LTM or ATM training [2·wk (immediately post RT), 1·wk (in isolation),
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60→85%VO2max, 250→500 kcal·session]. Additionally, 25 subjects volunteered for muscle
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biopsy prior to, and 24h-post acute exercise before and after training. Stable isotope labeling
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(70%2H2O, 3ml·kg-1) was utilized to quantify 24h-post exercise myofibrillar fractional synthesis
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rates (myoFSR). Mixed-model ANOVA revealed that RT-ATM, but not RT-LTM training
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produced greater chronic increases in lean mass than RT alone (p