日 内 分 泌 会 誌,(Folia
1177
Endocrinol.)68.1177∼1187.1992
II型 糖 尿 病 に お け る α2受容 体 機 能 に関 す る研 究 福 島県 立医 科大 学第 三 内科学教 室(指 導:福 地 田
Altered
Responses Growth
of Heart
Hormone
中
清
宣
Rate , Renal
to Clonidine
Sodium
in Type
Kiyonobu
総逸教 授)
Handling
II Diabetic
and Plasma Patients
TANAKA
The Third Department of Internal Medicine, Fukushima Medical College
The response and
to to
and
aim
of
the
clonidine
clarify
in
the
sodium
role
handling
(N)
were
enrolled
measured,
(p-cAMP),
renin at
clonidine
(150 ƒÊ when
classified
DM
Urinary PNE
and
DM-HR p - cAMP
p - cAMP and
N.
in
both
was
excretion did
N
not
(PRA),
Type
DM
decreased
after
markedly
in
the
clonidine with
or •çGH
NR
of
sodium
change
in
(FENa) DM-HR.
more
type
II
and
in
test
growth
was
To
hyper-response
than
that
,
oral
N,
was
determined.
hormone
of
subjects
improved.
(PNE)
with
DM
were
were
correlated
0.449,
in
On
cyclic
AMP
(p - GH)
were
administration
of (DM-HR,
and
the
similar
if not,
they
were
the
GH
three
DM-
in the
not
in
(the
(p
1177
Endocrinol.)68.1177∼1187.1992
II型 糖 尿 病 に お け る α2受容 体 機 能 に関 す る研 究 福 島県 立医 科大 学第 三 内科学教 室(指 導:福 地 田
Altered
Responses Growth
of Heart
Hormone
中
清
宣
Rate , Renal
to Clonidine
Sodium
in Type
Kiyonobu
総逸教 授)
Handling
II Diabetic
and Plasma Patients
TANAKA
The Third Department of Internal Medicine, Fukushima Medical College
The response and
to to
and
aim
of
the
clonidine
clarify
in
the
sodium
role
handling
(N)
were
enrolled
measured,
(p-cAMP),
renin at
clonidine
(150 ƒÊ when
classified
DM
Urinary PNE
and
DM-HR p - cAMP
p - cAMP and
N.
in
both
was
excretion did
N
not
(PRA),
Type
DM
decreased
after
markedly
in
the
clonidine with
or •çGH
NR
of
sodium
change
in
(FENa) DM-HR.
more
type
II
and
in
test
growth
was
To
hyper-response
than
that
,
oral
N,
was
determined.
hormone
of
subjects
improved.
(PNE)
with
DM
were
were
correlated
0.449,
in
On
cyclic
AMP
(p - GH)
were
administration
of (DM-HR,
and
the
similar
if not,
they
were
the
GH
three
DM-
in the
not
in
(the
(p
