VoL 27, No. 5 Printed in Japan
Gastroenterologia Japonica Copyright 9 1992 by The Japanese Society of Gastroenterology
Alanine aminotransferase and HCV-RNA responses following interferon therapy of HCV-RNA positive chronic hepatitis Yasuji ARASE 1, Hiromitsu KUMADA 1, Kazuaki CHAYAMA ~, Akihito TSUBOTA ~, Kenji IKEDA a, Satoshi SAITOH 1, Yoko SAKAI2, Toyomi MATSUMOTO2, and Mariko KOBAYASHI 2
1Department of Gastroenterology and 2Hepatic Research Unit, Toranomon Hospital, Tokyo, Japan Summary: Interferon (IFN) has been shown to be effective for chronic hepatitis C. This study investigated changes of alanine aminotransferase (ALT) and HCV-RNA in chronic hepatitis C patients treated with aIFN. IFN was given to 73 patients with HCV-RNA positive chronic hepatitis C. The pattern of changes in ALT activity after IFN aministration was classified into five types. Type 1 was characterized by normalization of ALT (
Gastroenterologia Japonica Copyright 9 1992 by The Japanese Society of Gastroenterology
Alanine aminotransferase and HCV-RNA responses following interferon therapy of HCV-RNA positive chronic hepatitis Yasuji ARASE 1, Hiromitsu KUMADA 1, Kazuaki CHAYAMA ~, Akihito TSUBOTA ~, Kenji IKEDA a, Satoshi SAITOH 1, Yoko SAKAI2, Toyomi MATSUMOTO2, and Mariko KOBAYASHI 2
1Department of Gastroenterology and 2Hepatic Research Unit, Toranomon Hospital, Tokyo, Japan Summary: Interferon (IFN) has been shown to be effective for chronic hepatitis C. This study investigated changes of alanine aminotransferase (ALT) and HCV-RNA in chronic hepatitis C patients treated with aIFN. IFN was given to 73 patients with HCV-RNA positive chronic hepatitis C. The pattern of changes in ALT activity after IFN aministration was classified into five types. Type 1 was characterized by normalization of ALT (
