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Osteoporos Int. Author manuscript; available in PMC 2016 July 26. Published in final edited form as: Osteoporos Int. 2016 February ; 27(2): 463–471. doi:10.1007/s00198-015-3236-5.
Age-associated declines in muscle mass, strength, power, and physical performance: impact on fear of falling and quality of life A. Trombetti1,2, K. F. Reid2, M. Hars1, F. R. Herrmann1, E. Pasha2, E. M. Phillips2, and R. A. Fielding2 A. Trombetti: [email protected]
Author Manuscript
1Division
of Bone Diseases, Department of Internal Medicine Specialties, Geneva University Hospitals and Faculty of Medicine, Rue Gabrielle-Perret-Gentil 4, CH-1211 Geneva 14, Switzerland 2Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
Abstract Summary—This 3-year longitudinal study among older adults showed that declining muscle mass, strength, power, and physical performance are independent contributing factors to increased fear of falling, while declines of muscle mass and physical performance contribute to deterioration of quality of life. Our findings reinforce the importance of preserving muscle health with advancing age.
Author Manuscript
Introduction—The age-associated loss of skeletal muscle quantity and function are critical determinants of independent physical functioning in later life. Longitudinal studies investigating how decrements in muscle components of sarcopenia impact fear of falling (FoF) and quality of life (QoL) in older adults are lacking. Methods—Twenty-six healthy older subjects (age, 74.1±3.7; Short Physical Performance Battery (SPPB) score ≥10) and 22 mobility-limited older subjects (age, 77.2±4.4; SPPB score ≥9) underwent evaluations of lower extremity muscle size and composition by computed tomography, strength and power, and physical performance at baseline and after 3-year follow-up. The Falls Efficacy Scale (FES) and Short Form-36 questionnaire (SF-36) were also administered at both timepoints to assess FoF and QoL, respectively.
Author Manuscript
Results—At 3-year follow-up, muscle cross-sectional area (CSA) (p
Osteoporos Int. Author manuscript; available in PMC 2016 July 26. Published in final edited form as: Osteoporos Int. 2016 February ; 27(2): 463–471. doi:10.1007/s00198-015-3236-5.
Age-associated declines in muscle mass, strength, power, and physical performance: impact on fear of falling and quality of life A. Trombetti1,2, K. F. Reid2, M. Hars1, F. R. Herrmann1, E. Pasha2, E. M. Phillips2, and R. A. Fielding2 A. Trombetti: [email protected]
Author Manuscript
1Division
of Bone Diseases, Department of Internal Medicine Specialties, Geneva University Hospitals and Faculty of Medicine, Rue Gabrielle-Perret-Gentil 4, CH-1211 Geneva 14, Switzerland 2Nutrition, Exercise Physiology, and Sarcopenia Laboratory, Jean Mayer Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
Abstract Summary—This 3-year longitudinal study among older adults showed that declining muscle mass, strength, power, and physical performance are independent contributing factors to increased fear of falling, while declines of muscle mass and physical performance contribute to deterioration of quality of life. Our findings reinforce the importance of preserving muscle health with advancing age.
Author Manuscript
Introduction—The age-associated loss of skeletal muscle quantity and function are critical determinants of independent physical functioning in later life. Longitudinal studies investigating how decrements in muscle components of sarcopenia impact fear of falling (FoF) and quality of life (QoL) in older adults are lacking. Methods—Twenty-six healthy older subjects (age, 74.1±3.7; Short Physical Performance Battery (SPPB) score ≥10) and 22 mobility-limited older subjects (age, 77.2±4.4; SPPB score ≥9) underwent evaluations of lower extremity muscle size and composition by computed tomography, strength and power, and physical performance at baseline and after 3-year follow-up. The Falls Efficacy Scale (FES) and Short Form-36 questionnaire (SF-36) were also administered at both timepoints to assess FoF and QoL, respectively.
Author Manuscript
Results—At 3-year follow-up, muscle cross-sectional area (CSA) (p
