HHS Public Access Author manuscript Author Manuscript
Menopause. Author manuscript; available in PMC 2017 June 01. Published in final edited form as: Menopause. 2016 June ; 23(6): 626–637. doi:10.1097/GME.0000000000000597.
Acupuncture in Menopause (AIM) Study: a Pragmatic, Randomized Controlled Trial Nancy E. Avis, PhD1, Remy R. Coeytaux, MD, PhD2, Scott Isom, MS3, Kristen Prevette, BA1, and Timothy Morgan, PhD3 1Department
of Social Sciences and Health Policy, Wake Forest School of Medicine, WinstonSalem, NC, USA
Author Manuscript
2Department
of Community and Family Medicine and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA 3Department
of Biostatistical Sciences, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC, USA
Abstract Objective—to evaluate the short- and long-term effects of acupuncture on vasomotor symptoms (VMS) and quality of life-related measures.
Author Manuscript
Methods—A total of 209 perimenopausal and postmenopausal women aged 45-60 experiencing ≥4 VMS per day recruited from the community and randomized to receive up to 20 acupuncture treatments within the first 6 months (acupuncture group) or the second 6 months (waitlist control group) of the 12-month study period. The primary outcome was mean daily frequency of VMS. Secondary outcomes were VMS interference with daily life, sleep quality, depressive symptoms, somatic and other symptoms, anxiety, and quality of life. Results—VMS frequency declined by 36.7% at 6 months in the acupuncture group and increased by 6.0% in the control group (p
Menopause. Author manuscript; available in PMC 2017 June 01. Published in final edited form as: Menopause. 2016 June ; 23(6): 626–637. doi:10.1097/GME.0000000000000597.
Acupuncture in Menopause (AIM) Study: a Pragmatic, Randomized Controlled Trial Nancy E. Avis, PhD1, Remy R. Coeytaux, MD, PhD2, Scott Isom, MS3, Kristen Prevette, BA1, and Timothy Morgan, PhD3 1Department
of Social Sciences and Health Policy, Wake Forest School of Medicine, WinstonSalem, NC, USA
Author Manuscript
2Department
of Community and Family Medicine and Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA 3Department
of Biostatistical Sciences, Wake Forest School of Medicine, Medical Center Blvd., Winston-Salem, NC, USA
Abstract Objective—to evaluate the short- and long-term effects of acupuncture on vasomotor symptoms (VMS) and quality of life-related measures.
Author Manuscript
Methods—A total of 209 perimenopausal and postmenopausal women aged 45-60 experiencing ≥4 VMS per day recruited from the community and randomized to receive up to 20 acupuncture treatments within the first 6 months (acupuncture group) or the second 6 months (waitlist control group) of the 12-month study period. The primary outcome was mean daily frequency of VMS. Secondary outcomes were VMS interference with daily life, sleep quality, depressive symptoms, somatic and other symptoms, anxiety, and quality of life. Results—VMS frequency declined by 36.7% at 6 months in the acupuncture group and increased by 6.0% in the control group (p
