J Interv Card Electrophysiol (2015) 42:173–326 DOI 10.1007/s10840-015-9975-6

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Special Program and Abstract issue of the 11th Annual Congress of the European Cardiac Arrhythmia Society (ECAS) April 19-21, 2015 Paris, France Hotel Meriden-Etoile Guest Editor: Prof. Samuel Lévy, MD Aix-Marseille Université, Marseille, France

ECAS Scientific Program

PROGRAM AT A GLANCE 11th Annual Congress of the European Cardiac Arrhythmia Society SCIENTIFIC PROGRAM OF PRE-ARRANGED SESSIONS ECAS 2015 ABSTRACT SESSIONS 1–4 Sunday, April 19, 2015, 10:30 AM–12:00 PM Abstract Session 1: Atrial fibrillation ablation Abstract Session 2: Sudden cardiac death. Prevention and management Abstract Session 3: Atrial fibrillation and prevention of related thromboembolism Abstract Session 4: Mechanisms of ventricular arrhythmias ECAS 2015 ABSTRACT SESSIONS 5–8 Monday, April 20, 2015, 10:30 AM–12:00 PM Abstract Session 5: Advances in atrial fibrillation ablation II Abstract Session 6: Cardiac resynchronization therapy: techniques and outcome Abstract Session 7: Mapping and ablation of ventricular arrhythmias Abstract Session 8: Clinical and genetic aspects of ARVD/C ECAS 2015 ABSTRACT SESSIONS 9–12 Tuesday, April 21, 2015, 08:30 AM–10:00 AM Abstract Session 9: Atrial fibrillation mechanisms and management I Abstract Session 10: Atrial arrhythmia mechanisms II Abstract Session 11: Management of atrial arrhythmias Abstract Session 12: Atrial fibrillation ablation III

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ECAS 2015 POSTER SESSION A: PARTS 1 AND 2 Part 1: Supraventricular arrhythmias. Advances in mechanisms and management Part 2: Atrial fibrillation characteristics and management ECAS 2015 POSTER SESSION B: PARTS 1 AND 2 B Part 1: Arrhythmias and heart disease Techniques and tools B Part 2: Atrial fibrillation ablation Screening athletes ECAS 2015 POSTER SESSION C: PARTS 1 AND 2 Part 1: Cardiac resynchronization therapy Arrhythmia mechanisms Part 2: Sudden cardiac death and implantable cardioverter defribrillator ECAS 2015 POSTER SESSION D: PARTS 1 AND 2 Part 1: Pacing and related complications Atrial fibrillation and anticoagulant therapy Part 2: Syncope Ablation of ventricular arrhythmias

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Invitation Dear Colleagues, This is an invitation to join us at the 11th Annual Scientific Congress of the European Cardiac Arrhythmia Society “ECAS 2015” to be held in Paris, France April 19 to 21, 2015, at the Meridien-Etoile Hotel (Porte Maillot). All those who attended previous editions of ECAS Congress know that it is a highly scientific and educational event in a cheerful atmosphere which facilitates interaction between the renowned faculty and the audience which is particularly appreciated by fellows. This edition promises to be successful and we will be delighted to have you among us in Paris next April.

Riccardo Cappato, MD

Nicolas Lellouche, MD

Xavier Jouven, MD

President of ECAS

Congress Chairman

Scientific Program chair

EXECUTIVE COMMITTEE OF THE EUROPEAN CARDIAC ARRHYTHMIA SOCIETY President

Riccardo Cappato (Milan, IT)

Past President

Wyn Davies (London, GB)

Vice-President (Education and Research)

Richard Hauer (Utrecht, NL)

Vice-President (National Societies)

Massimo Santini (Rome, IT)

Vice-President (International Societies and EU)

Samuel Lévy (Marseille, FR)

Treasurer

Eli Ovsyshcher (Beersheba, IL)

Secretary General Continuing Medical Education

Leo Van Wersch (Paris, FR) Nicholas Peters (London, GB)

Relation with European Societies

Stefan Kaab (Munich, DE)

Chair Membership Program

Neil Sulke (Eastbourne, GB)

Organizing annual Congress Education Committee

Gerhard Steinbeck (Munich, DE) Thorsten Lewalter (Munich, DE)

Organizing Committee ECAS 2015

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Gerhard Steinbeck MD

177

Samuel Levy MD

Nicolas Lellouche, MD

Program Committee Andrey Ardashev; Alawi Alsheikh-Ali; Serge Barold; Leonardo Calo; David S Cannom; Riccardo Cappato; Sumeet Chugh; Wyn Davies; Roberto De Ponti; Heidi Estner; Jeronimo Farre; Mark Estes III; John Fisher; Robert Hatala; Richard Hauer; Ellen Hoffmann; Charles Jazra; Xavier Jouven (Chair); Stefan Kääb; Jean-François Leclercq; Gilles Lascault; Samuel Lévy; Thorsten Lewalter; Jean-Yves Le Heuzey; Shaowen Liu; Peter Loh; Pierpaolo Lupo; Chang Sheng Ma; Michaël Näbauer; Mohan Nair; Yuji Nakazato; Andrea Natale; Petr Neuzil; Promund Obel; Eli Ovsyshcher; Douglas L Packer; Luigi Padeletti; Nicholas S. Peters; Dubravko Petrac; Antonio Raviele; Amiran Revishvilli; Sanjeev Saksena; Richard Schilling; Gerhard Steinbeck; Massimo Santini; Neil Sulke; Dorwarth Uwe; Reza Wakili; Bruce Wilkoff. Scientific Advisory Board Masood Akhtar (Milwaukee, USA)

Bulent Gorenek (Eskisehir, TR)

Bertil S. Olsson (Lund, SE)

Etienne Aliot (Nancy, FR)

Stephen C. Hammill (Rochester, USA)

Oscar Oseroff (Buenos Aires, AR)

Maurits A. Allessie (Maastricht, NL)

Richard Hauer(Utrecht, NL)

Ali Oto (Ankara, TR)

Eckhard Alt (Munich, DE)

Habib Haouala (Tunis, TN)

Eli Ovsyshcher (Beersheba, IL)

Charles Antzelevitch (Utica, USA)

Yoshito Iesaka (Tokyo, JP)

Douglas L. Packer (Rochester, USA)

Andrey Ardashev (Moscow, RU)

Michiel Janse (Amsterdam, NL)

Luigi Padeletti (Florence, IT)

Serge S. Barold (Boca Raton, USA) David Benditt (Minneapolis, USA)

Charles Jazra (Beirut, LB) Xavier Jouven (Paris, FR)

Nicholas S Peters, (London, GB) Dubravko Petrac (Zagreb, HR)

Poul Erik Bloch-Thomsen (Hellerup, DK)

Werner Jung (Villingen, DE)

Eric N. Prystowsky (Indianapolis, USA)

Jozsef Borbola (Budapest, HU)

Stefan Kääb (Munich, DE)

Antonio Raviele(Venice, IT)

Johannes Brachmann (Coburg, DE)

Prapa Kanagaratnam (London, GB)

Amiran Revishvili (Moskow, RU)

A John Camm (London, GB)

Joergen Kanters (Copenhagen, DK)

Dwight Reynolds (Oklahoma, USA)

Alessandro Capucci (Ancona, IT) Riccardo Cappato (Milan, IT)

Bondo Kobulia (Tbilisi, GE) Karl-Heinz Kuck (Hamburg, DE)

Edward Rowland (London, GB) Sanjeev Saksena (New Brunswick, USA)

David S. Cannom (Los Angeles, USA)

Jean-François Leclercq (Paris, FR)

Massimo Santini (Rome, IT)

Sumeet Chugh (Los Angeles, USA)

Jean-Yves Le Heuzey (Paris, FR)

Maurizio Santomauro (Naples, IT)

Antonio Curnis (Brescia, IT)

Samuel Lévy (Marseille, FR)

Dipen Shah (Geneva, CH)

Philippe Coumel*

Berndt Luderitz (Bonn, DE)

Richard Schilling (London, GB)

D. Wyn Davies (London, GB)

Damian Gascon Lopez (Sevilla, ES)

Georg Schmidt (Munich, DE)

Hu Dayi (Beijing, CN)

Marek Malik (London, GB)

Jabir Sra (Milwaukee, USA)

Luc De Roy (Yvoir, BE)

Harry G. Mond (Melbourne, AU)

Gerhard Steinbeck (Munich, DE)

Sergio Dubner (Buenos Aires, AR)

Alessandro A Montenero (Rome, IT)

Neil Sulke (Eastbourne, GB)

Nils G. Edvardsson (Goteborg, SE)

Conception Moro Serrano (Madrid, ES)

Paul Touboul (Lyon, FR)

Michaël Eldar (Tel Aviv, IL)

Arthur J. Moss (Rochester, NY, USA)

Albert Waldo (Cleveland, USA)

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178 (continued) Nabil El-Sherif (New York, USA) Jeronimo Farre (Madrid, ES) John Fisher (New-York, USA) Guy Fontaine (Paris, FR) Robert Frank (Paris, FR) Seymour Furman (New York, USA)*

Michael Nabauer (Munich, DE) Gerald V. Nacarelli (Hershey, USA) Yuji Nakazato (Tokyo, JP) Andrea Natale (Cleveland, USA) Promound I. W.Obel (Johannesburg, ZA) Brian Olshansky (Iowa City, USA)

Hein JJ Wellens (Maastricht, NL) Bruce Wilkoff (Cleveland, USA) David Wilber (Chicago, USA) George D. Wyse (Calgary, CA)

*In memoriam Abstract Selection Each abstract has been sent to eight reviewers and been evaluated by a minimum of four of them. The organizing committee would like to thank the abstract reviewers for their valuable help in the abstract selection for the ECAS 2015 program: Etienne Aliot; Elad Anter; Serge Barold; Jean-Jacques Blanc; Poul-Erik Block Thomsen; Gerard Boink; Gunter Breithardt; Hugh Calkins; Leonardo Calo; John Camm; Riccardo Cappato; Mario Delmar; Roberto De Ponti; Luigi Di Biase; Nils Edvardsson; Nabil El Sherif; Mark Estes; Heidi Estner; Gerard Guiraudon; Sam Hanon; Richard Hauer; Bengt Herweg; Ellen Hoffman; Carsten Israel; Michiel Janse; Prapa Kanagaratnam; Helmut Klein; Yusuke Kondo; Jean-Yves Le Heuzey; Nicolas Lellouche; Thorsten Lewalter; Berndt Lüderitz; Marek Malik; Robert Myerburg; Yuji Nakazato; Brian Olshansky; Ali Oto; Eli Ovshyscher; Dubravko Petrac; Sanjeev Saksena; Walid Saliba; Massimo Santini; Peter Schwartz; Robert Schweikert; Dipen Shah; Claudio Shuger; Jasbir Sra; Gerhard Steinbeck; Neil Sulke; Richard Sutton; Tamas Szili-Torok; Jacob Tfelt-Hansen; Antonello Vado; Peter Van Tintelen; Reza Wakili; Albert Waldo; David Wilber; Bruce Wilkoff; Roger Winkle.

General Information Congress Venue LE MERIDIEN ETOILE Hôtel 81 Boulevard Gouvion Saint Cyr, 75848 Paris Cedex 17 Tel: (33) (0)1 40 68 34 34 www.lemeridienetoile.com Congress Chairman Nicolas Lellouche, MD Secretary: Hôpital Henri Mondor 51 avenue du Maréchal de Lattre De Tassigny 94000 Créteil, France Email: [email protected]

Sandrine Bordière Tel: +33149 814350 Email: [email protected]

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Abstract Awards Awards for the best oral abstracts will be presented during the opening ceremony to take place on Sunday April 19, 2015, at Room Derain Presentation of the awards for best poster presentations will take place on Tuesday April 21, 2015, 12:00 PM–12:30 PM Room Diderot (Meridien-Etoile Hotel) 11th Philippe Coumel Lecture 2015 Will be presented on Sunday April 19, 2015, from 5:30 PM to 6:00 PM as part of the opening ceremony Badges Badges and Final program will be available for pre-registered participants and faculty at the ECAS welcome desk, Hotel Meridien Etoile, Paris, starting Sunday April 19, 2015, from 2:00 PM to 6:00 PM ECAS Congress Secretariat Josette Razafimbelo Tel/FAX: + 33 (0)4 89 14 45 33 Cell: +336 26 07 55 74 E-mail: [email protected] Registration Registration and payment of Congress fees as well as payment of membership dues can be done through the website. Registration on site will start on Sunday April 19, 2015, at 8:00 AM at Hotel Meridien-Etoile. Currency Payment in cash for registration on site must be made in euros only. Payment using Visa credit cards will be accepted on the Congress site. Personal checks cannot be accepted. Congress Website All information, Scientific Program and registration to the congress, abstract submission and membership subscription with secured payment can be done through our website http://www.ecas-heartrhythm.org Pre-Arranged Sessions The program includes 33 pre-arranged sessions and workshops or debates. It can be downloaded from our website as well as the program of abstracts selected for oral or poster presentations

Publications

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Sanjeev Saksena MD JICE Editor-in-Chief

Leonardo Calo MD

Abstract Presentations The abstracts accepted for oral or poster presentation will be published in a supplement issue of the Journal of Interventional Cardiac Electrophysiology (JICE), the official journal of ECAS provided the authors attend the congress and present their work. The oral presentation of abstracts is 10 min plus 5 min for discussion. All posters accepted for presentation will be chaired. Please check the day and time at which your poster will be presented to the chairpersons and the time at which the presenter should be near their poster board.

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PROGRAM AT A GLANCE ECAS 2015 SUNDAY APRIL 19, 2015 8:00am 5:00pm

Registration Concurrent Workshops

8:30am 10:00am

Room TBA

Room PASCAL

Room DIDEROT

Session WS-06

Session WS-01

Session WS-02

Atrial Fibrillation ablation D L Packer

Cardiac Resynchronization therapy Bruce Wilkoff

Session WS-03 Pacemaker, ICD and CRT:Case studies S Barold E Ovsyshcher C Israel B Herweg

Five year Experience with NOACs

Room DESCARTES

Chaired poster session A 8:30-12:00

Coffee break Concurrent Abstract Sessions 10:30am 12:00pm

2:00pm 3:30pm

Room DERAIN

Room DIDEROT

Room DESCARTES

Room PASCAL

Room GAUGUIN

Oral Abstract 1

Oral Abstract 2

Oral Abstract 3

Oral Abstract 4

Session A cont.

12:150pm-1:45pm

12:15pm-1:45pm

Seated Luncheon Panel 1

Seated Luncheon Panel 2

Room DERAIN

Room DIDEROT

Session AB-01

Session HD-01

Pulmonary Vein Isolation and related strategies

Inherited potentially lethal syndromes

Room DESCARTES

Room PASCAL

Room GAUGUIN

Session SP-07 Session SP-02 ECAS-WSA New frontiers in cardiac pacing

Session B

Prevention of sudden cardiac death

Chaired poster

Room PASCAL

Room GAUGUIN

3:30pm - 4:00pm: Coffee break and visit to posters Room DERAIN

Room DIDEROT

Room DESCARTES

Session SP-03

Session SP-04

Session AB-02 4.00pm 5:30pm

5:30pm

Ventricular tachycardia ablation (I)

The MADIT Trials

Intracardiac imaging

Session SP-05 Stroke prevention in atrial fibrillation

Room DERAIN Special lecture: A tribute to Philippe Coumel

Session B Chaired poster

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6:00pm

Opening ceremony

Chaired By Prof. Samuel LEVY (Marseille, FR) and Prof. Gerhard Steinbeck (Munich, DE) and OUTSTANDING ACHIEVEMENT AWARDS Presented by Dr Riccardo Cappato (Milan, IT) President of ECAS Prof. Nicolas Lellouche (Paris, FR) Congress Chairman Dr Fernand Hessel (Mulhouse, FR) President Lucien Dreyfus Foundation

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MONDAY APRIL 20, 2015

8:30am 10:00am

Room COROT

Room DIDEROT

Room DESCARTES

Room PASCAL

Room GAUGUIN

Session SP-06

Session SP-07

HRS-ECAS Session I Session AB-03

Session C

AF: beyond stroke prevention

Sudden cardiac Arrhythmogenic death : and left ventricular Cardiomyopathy I hypertrophy (LVH)

catheter ablation of complex arrhythmias

Chaired posters

10:00am - 10:30am: Coffee break and visit to the posters Concurent Oral Abstract sessions Room COROT

Room DIDEROT

Room DESCARTES

Room PASCAL

Oral abstract 5

Oral abstract 6

Oral abstract 7

Oral abstract 8

10:30am 12:00pm

12:15pm-1:45pm

12:15pm-1:45pm

Luncheon Panel 3

Luncheon Panel 4

Room COROT

2:00pm 3:30pm

Room DIDEROT

Room DESCARTES

Room PASCAL

Chaired Posters (cont.)

Room GAUGUIN

Session HD-06 Session AB-04 Current issues in atrial fibrillation

Session HD-07 Biomarker-based HRS-ECAS Session therapeutic Arrhythmogenic decision making in Cardiomyopathy II AF

Session SP-15 Approaches in VT Ablation

Session D Chaired poster

3:30pm - 4:00pm: Coffee break and visit to the posters Simultaneous sessions

4:00pm 5:30pm

Room COROT

Room DIDEROT

Room DESCARTES

Room PASCAL

Room GAUGUIN

Session AB-05

SP-14

Session SP-13

Session HD-04

Session D

AF ablation not targetting pulmonary veins

8th Japan HRSECAS CRT therapy Y. Nakazato

Automatic nervous Sudden cardiac death system and arrhythmias

Chaired poster

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TUESDAY APRIL 21, 2015

8:30am 10:00am

Room DIDEROT

Room DESCARTES

Room PASCAL

Room TBA

Oral abstract 9

Oral abstract 10

Oral abstract 11

Oral abstract 12

Room DESCARTES

Room PASCAL

Room TOCQUEVILLE

10:00am - 10:30am: Coffee break Room DIDEROT Session SP-11 10:30am 12:00pm

12:00pm 12:30pm

Unresolved questions

Session SP-12

Session WS-05 Session WS-04

New tools and techniques Current Issues in AF in cardiac arrhythmias for AF management

Abstract Poster AWARDS

Nightmares in catheter ablation

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SATURDAY APRIL 18, 2015 REGISTRATION from 2:00 PM to 5:00 PM Hotel Meridien Etoile (Lobby) SCIENTIFIC SESSIONS SUNDAY APRIL 19, 2015 8:30 AM–10:00 AM ROOM TBA WS-06 Five Year Experience with NOACs: Time for a First Review Chairpersons: Jean-Yves Le Heuzey (Paris, FR), Riccardo Cappato (Milan, IT) 1. NOACs in venous thromboembolism Giancarlo Agnelli (Perugia, IT) 2. Stroke prevention of AF: Respective indications of NOAcs versus LAA device closure Samuel Lévy (Marseille, FR) 3. NOACs in catheter ablation Wyn Davies (London, GB) 4. NOACs in cardioversion Riccardo Cappato (Milan, IT) SUNDAY APRIL 19, 2015 8:30 AM–10:00 AM ROOM PASCAL Workshop WS-01 Atrial Fibrillation Ablation: A New Generation of Approaches Chairpersons: Douglas L. Packer (Rochester, USA), Karl-Heinz Kuck (Hamburg, DE) 1. Linear cold balloon therapy for persistent atrial fibrillation Suraj Kapa (Rochester, USA) 2. Impact of Contact Force Ablation on Clinical Outcomes in Patients with Atrial Fibrillation Dipen Shah (Geneva, CH) 3. 4–5 D Mapping for Intracardiac and Extracorporeal Ablation of AF David Wilber (Maywood, USA) 4. The Biophysics of New Generation Cryoballoon and Contact Source Ablative Intervention Douglas L. Packer (Rochester, USA) SUNDAY APRIL 19, 2015 8:30 AM–10:00 AM ROOM DIDEROT Workshop WS-02

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Cardiac Resynchronization Therapy Improving Outcomes and Reducing Adverse events Chairpersons: Bruce Wilkoff (Cleveland, USA), Helmut Klein (Munich, DE) 1. Pre-operative assessment of CRT Responsiveness Bruce L. Wilkoff MD 2. Impact of RV pacing vs prevention of dyssynchrony Jean-Jacques Blanc (Brest, FR) 3. Approaches to upgrading vs avoiding CRT Mark Estes III (Boston, USA) 4. Management of atrial fibrillation in CRT Patients: PVI or AV junctional ablation Walid Saliba (Cleveland, USA) 5. Alternatives to the CS for left ventricular pacing Tamas Szili-Torok (Rotterdam, NL) SUNDAY APRIL 19, 2015 8:30 AM–10:00 AM ROOM DESCARTES Workshop WS-03 Pacemaker ECG, ICD and CRT interpretation: Case studies Chairpersons: Serge Barold (Tampa, USA), Eli Ovsyshcher (Beersheba, IL), Carsten Israel (Bielefeld, DE), Bengt Herweg (Tampa, USA) SUNDAY APRIL 19, 2015 8:30 AM–12:00 PM ROOM GAUGUIN Chaired poster session A SUNDAY APRIL 19, 2015 10:30 AM–12:00 PM: Concurrent Abstract oral sessions ROOM DERAIN Abstract session 1 ROOM DIDEROT Abstract session 2 ROOM DESCARTES Abstract session 3 ROOM PASCAL Abstract session 4

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Luncheon Panels 12:15 PM–1:45 PM Seated Luncheon Panel 1

SUNDAY APRIL 19, 2015 2:00 PM–3:30 PM ROOM DERAIN Session AB-01 Pulmonary vein isolation and related strategies Chairpersons: Douglas Packer (Rochester, USA), Wyn Davies (London, GB) 1. AF mechanisms and role of pulmonary veins in various AF presentations Karl-Heinz Kuck (Hamburg, DE) 2. Periprocedural dormant conduction after PV isolation: how does it affect AF recurrence? Heidi Estner (Munich, DE) 3. Do catheter techniques make a difference in success rates? Leonardo Calo (Rome, IT) 4. Role of autonomic ganglia in AF ablation success rates Yusuke Kondo (Chiba, JP) SUNDAY APRIL 19, 2015 2:00 PM–3:30 PM ROOM DIDEROT HD-01 Update on inherited potentially lethal syndromes Chairpersons: Peter Schwartz (Pavia, IT), Hugh Calkins (Baltimore, USA) 1. Long QT syndrome Peter Schwartz (Pavia, IT) 2. Cathecholaminergic polymorphic VT Jacob Tfelt-Hansen (Copenhagen, DK) 3. Brugada syndrome Herve Le Marec (Nantes, FR) 4. Early repolarization syndrome Juhani Junttila (Oulu, FI)

12:15 PM–1:45 PM Seated Luncheon Panel 2

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SUNDAY APRIL 19, 2015 2:00 PM–3:30 PM ROOM DESCARTES SP-07 Joint session of ECAS-WSA (World Society of Arrhythmology) The new frontiers in cardiac pacing Chairpersons: Massimo Santini (Rome, DE), Eli Ovsyshcher (Beer Sheba, IL) 1. 50 years of cardiac pacing: where are we now? João Rodrigues de Sousa (Lisbon, PT) 2. The leadless pacemaker Antonio Curnis (Brescia, IT) 3. Multipoint pacing to optimize CRT outcome Antonello Vado (Cuneo, IT) 4. Remote control: from device to patient management Xavier Viñolas (Barcelona, ES) 5. Advances in biological pacing Gerard Boink (Amsterdam, NL) SUNDAY APRIL 19, 2015 2:00 PM–3:30 PM ROOM PASCAL Session SP-02 Prevention of sudden cardiac death in heart disease Chairpersons: David Cannom (Los Angeles, USA), Poul Erik Bloch-Thomsen (Copenhagen, DK) 1. Effectiveness of Automatic External Defibrillators: availability and employability Alessandro Capucci (Ancona, IT) 2. Indications and effectiveness of wearable ICDs Johannes Brachmann (Coburg, DE) 3. What have we learned from prophylactic ICD trials? Robert Myerburg (Miami, USA) 4. What have we learned from ICD registries? Robert Hauser (Minneapolis, USA) SUNDAY APRIL 19, 2015 2:00 PM–3:30 PM ROOM GAUGUIN Chaired Poster session B

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3:30 PM–4:00 PM Coffee break and Posters SUNDAY APRIL 19, 2015 4:00 PM–5:30 PM ROOM DERAIN Session AB-02 Issues in ventricular tachycardia ablation (I) Chairpersons: Nicholas Peters (London, DE), Jasbir Sra (Milwaukee, USA) 1. New insights into the VT substrate using the Rhythmia System Elad Anter (Boston, USA) 2. Functional characterization of VT scar by ripple mapping Prapa Kanagaratnam (London, GB) 3. Epicardial ablation of VT Katja Zeppenfeld (Leiden, NL) 4. Ablation of bundle branch and fascicular ventricular tachycardia Jasbir Sra (Milwaukee, USA) SUNDAY APRIL 19, 2015 4:00 PM–5:30 PM ROOM DIDEROT SP-03 The MADIT (Multicenter Automatic Defibrillator Implantation) Trials Chairpersons: David Cannom (Los Angeles, USA), Luigi Padeletti (Florence, IT) 1. Long-term prognosis of MADIT-CRT patients: new data Mark Estes III (Boston, USA) 2. MADIT-CHAGAS study: design and early data Claudio Schuger (Detroit, USA) 3. MADIT-CHIC study: design and early data Jagmeet P. Singh, (Boston, USA) 4. Importance of LBBB in predicting a positive response to CRT therapy in Class I/II heart failure David S. Cannom (Los Angeles, USA) 5. Impact of type II diabetes on the prognosis of coronary patients with heart failure: what would an ICD trial look like in this patient group? Helmut Klein (Munich, DE)

SUNDAY APRIL 19, 2015 4:00 PM–5:30 PM

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Room DESCARTES SP-04 Advances in Intracardiac Imaging for Interventional Electrophysiologists: 2015 and beyond Chairpersons: Andrea Natale (Austin, USA), Roger Winkle (Palo Alto, USA) 1. Cardiac CT for definition of left atrial appendage morphology and risk stratification Luigi Di Biase (New York, USA) 2. Intracardiac echocardiography performed from and for the pulmonary vasculature—technique and application Sanjeev Saksena (Warren, USA) 3. Magnetic resonance imaging of the atrial substrate and progression of atrial fibrillation: a critical analysis Mark O’Neill (London, GB) 4. Real-time three dimensional imaging of cardiac chambers Mohammad Shenasa (San Jose, USA) SUNDAY APRIL 19, 2015 4:00 PM–5:30 PM Room PASCAL SP-05 Stroke prevention in atrial fibrillation Chairpersons: John Camm (London, GB), Johannes Brachmann (Coburg, DE) 1. NOACs—5 years after RE-LY: What have we learned? Michael Näbauer (Munich, DE) 2. Interventional therapy by occluder devices—which patients should be considered? Thorsten Lewalter (Munich, DE) 3. Ablation therapy for stroke prevention in patients with AF John Fisher (New York, USA) 4. Role of continuous rhythm monitoring—identification of cause or bystander? Albert Waldo (Cleveland, USA) SUNDAY APRIL 19, 2015 3:30 PM–5:00 PM ROOM GAUGUIN Chaired poster session B (Cont.) Room DERAIN 5:30 PM to 6:00 PM Special lecture: A tribute to Philippe Coumel TBA

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Opening ceremony Prof. Samuel Lévy (Marseille, FR) and Prof. Gerhard Steinbeck (Munich, DE) Outstanding Achievement Awards Best Abstracts Awards Presented by Dr Riccardo Cappato (Milan, IT) President of ECAS Prof. Nicolas Lellouche (Paris, FR) Congress Chairman Dr Fernand Hessel (Mulhouse, FR) President Lucien Dreyfus Foundation Followed by a cocktail reception MONDAY APRIL 20, 2015 08:30 AM–10:00 AM ROOM COROT SESSION SP-06 Atrial Fibrillation: Beyond Stroke Prevention Chairpersons: Nils Edvardsson (Gothenburg, SE), Amiran Revishvili (Moscow, RU) 1. Cardiovascular Morbidity and Mortality of AF Christine Albert (Boston, USA) 2. Atrial Fibrillation and Sudden Cardiac Death Eloi Marijon (Paris, FR) 3. Role of Pharmacology Juan Tamargo (Madrid, ES) 4. Role of Catheter Ablation Walid Saliba (Cleveland, USA) MONDAY APRIL 20, 2015 08:30 AM–10:00 AM ROOM DIDEROT Session SP-07 Sudden cardiac death: Focus on at risk patients with secondary left ventricular hypertrophy (LVH) Chairpersons: John Fisher (New-York, USA), Dubravko Petrac (Zagreb, HR)

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ECG and MRI criteria of LVH James Harrison (London, GB) Mechanism of ventricular arrhythmias in patients with LVH Nabil El-Sherif (New York, USA) Risk stratification of patients with LVH at risk of sudden cardiac death Gerhard Steinbeck (Munich, DE) Regression of LVH and clinical outcome Ariel Cohen (Paris, FR) MONDAY APRIL 20, 2015 08:30 AM–10:00 AM ROOM DESCARTES Session HD-03 HRS-ECAS SPECIAL SESSION I Arrhythmogenic Cardiomyopathy I Diagnosis and Mechanisms Chairpersons: Peter Van Tintelen (Amsterdam, NL), Connie Bezzina (Amsterdam, NL) History of the disease Guy Fontaine (Paris, Fr) Advantages/limitations of the Revised Task Force Criteria Richard Hauer (Utrecht, NL) Pathogenicity of genetic variants Dennis Dooijes (Utrecht, NL) Role of substructures in the Intercalated disk Mario Delmar (New York, USA) MONDAY APRIL 20, 2015 08:30 AM–10:00 AM ROOM PASCAL AB-03 Highly technologic approach in catheter ablation of complex arrhythmias Chairpersons: Richard Schilling (London, GB), Andrey Ardashev (Moscow, RU) 1. 3-D mapping and contact force sensing in ablation of atrial fibrillation Roberto De Ponti, (Varese, IT) 2. Remote navigation ablation of atrial fibrillation and flutter using remote manipulation of multiple catheters Eugene Crystal (Toronto, CA)

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3. Preprocedural imaging and 3-D mapping in patients with ventricular tachycardia associated with structural heart disease Richard Schilling (London, GB) 4. 3-D mapping and contact force sensing in ablation of idiopathic ventricular tachycardia David Wilber (Chicago, USA) MONDAY APRIL 20, 2015 08:30 AM–10:30 AM ROOM GAUGUIN Chaired Poster session C Part 1 10:00 AM–10:30 AM Coffee break and Posters MONDAY APRIL 20, 2015 10:30 AM–12:00 PM Concurrent Oral Abstract sessions ROOM COROT Abstract session 5 ROOM DIDEROT Abstract session 6 ROOM DESCARTES Abstract session 7 ROOM PASCAL Abstract session 8

12:15 PM–1:45 PM Room Dufy

12:15 PM–1:45 PM

Luncheon Panel 3

Luncheon Panel 4

MONDAY APRIL 20, 2015 2:00 PM–3:30 PM ROOM COROT SESSION AB-04 Current issues in atrial fibrillation Chairpersons: Antonio Raviele (Venice, IT), Leonardo Calo (Rome, IT) TBC Patients Selection: Do we already need updated guidelines? Riccardo Cappato (Milan, IT) Periprocedural Anticoagulation for AF ablation with warfarin and NOACs: beyond clinical stroke prevention Etienne Aliot (Nancy, FR)

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Energy Sources and tools: To whom, when and why? New generation cryothermia balloon Ellen Hoffmann (Munich, DE) Laser balloon ablation Thomas Deneke (Bad Neustadt, DE) Lesion visualization and future directions Matthew Wright (London, GB) MONDAY APRIL 20, 2015 2:00 PM–3:30 PM ROOM DIDEROT SESSION: HD-06 Biomarker-based therapeutic decision making in atrial fibrillation Chairpersons: Stefan Kääb (Munich, DE), Nicholas Peters (London, GB) Biosignals—AF complexity guiding treatment strategies? Ulrich Schotten (Maastricht, NL) Biomarkers for the patient at risk for AF Moritz Sinner (Munich, DE) Genetics of AF—Ready for clinical decision making? Stefan Kääb (Munich, DE) MicroRNAs—Potential biomarkers for AF and AF therapy? Reza Wakili (Munich, DE) MONDAY APRIL 20, 2015 2:00 PM–3:30 PM ROOM DESCARTES HD-07 HRS-ECAS SPECIAL SESSION ECAS-HRS Joint Special Session (organized by Richard Hauer) Arrhythmogenic Cardiomyopathy II Risk Stratification and Therapy Chairpersons: Corrina Brunckhorst (Zurich, CH), Richard Hauer (Utrecht, NL) 1. Electrophysiologic substrate and risk stratification Alessandro Zorzi (Padova, IT) 2. Long-term Follow-up of ICD Therapy in ARVD/C Hugh Calkins (Baltimore, USA)

J Interv Card Electrophysiol (2015) 42:173–326

J Interv Card Electrophysiol (2015) 42:173–326

3. Towards Elimination of the Electrophysiologic Substrate Francis Marchlinski (Philadelphia, USA) 4. Towards New Drug Therapy Jeffrey Saffitz (Boston, USA) MONDAY APRIL 20, 2015 2:00 PM–3:30 PM ROOM PASCAL SP-15 Approaches in VT Ablation Chairpersons: Francis Marchlinski (Philadelphia, USA), Walid Saliba (Cleveland, USA) 1. Mechanisms of VT in structural heart disease Michiel Janse (Amsterdam, NL) 2. Ischemic cardiomyopathy: The homogenization approach Andrea Natale (Austin, USA) 3. VT ablation in non-ischemic cardiomyopathy Jasbir Sra (Milwaukee, USA) 4. The impact of pre and post VT ablation inducibility on long-term success, re-hospitalization and mortality. Gerhard Hindricks (Leipzig, DE) MONDAY APRIL 20, 2015 2:00 PM–5:00 PM ROOM GAUGUIN Chaired Poster presentation D 3:30 PM–4:00 PM Coffee break and Posters MONDAY APRIL 20, 2015 4:00 PM–5:30 PM ROOM COROT AB-05 AF ablation techniques not targeting the pulmonary veins Chairpersons: Riccardo Cappato (Milan, IT), David Wilber (Maywood, USA) 1. Detection and role of non-pulmonary vein AF triggers Richard Schilling (London, GB) 2. Targeting complex fractionated atrial electrograms Julien Seitz (Marseille, FR)

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3. Mapping techniques for detecting rotors Omer Berenfeld (Ann Arbor, USA) 4. Rotors-based AF ablation strategies Paul Wang (Stanford, USA) MONDAY APRIL 20, 2015 4:00 PM–5:30 PM ROOM DIDEROT SP-14 8th Japanese HRS/ECAS SYMPOSIUM New Insights in CRT therapy Chairpersons: Yuji Nakazato (Chiba, JP), Gilles Lascault (Paris, FR) 1. Impact of multisite LV pacing in heart failure patients Werner Jung (Villingen, DE) 2. Trans-septal endocardial LV pacing Hidemori Hayashi (London, GB) 3. Role of surgical approach: An update Katsuhiko Imai (Hiroshima, JP) 4. Clinical efficacy of optimization algorithm Toshiiyuki Ishikawa (Yokohama, JP) MONDAY APRIL 20, 2015 4:00 PM–5:30 PM ROOM DESCARTES SP-13 Sudden cardiac death on a population level—Stratification methods for the patient with ejection fraction >35 % Chairpersons: Stefan Kääb (Munich, DE), Brian Olshansky (Iowa City, USA) 1. Epidemiology of SCD Xavier Jouven (Paris, FR) 2. ECG—Risk stratification for SCD Pieter Postema (Amsterdam, NL) 3. Holter-ECG: Potential parameters for risk stratification Marek Malik (London, GB) TBC 4. Genetics of SCD—What have we learned? Vincent Probst (Nantes, FR)

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MONDAY APRIL 20, 2015 4:00 PM–5:30 PM ROOM PASCAL HD-04 Role of the autonomic nervous system in cardiac arrhythmias Chairpersons: Gunter Breithardt (Muenster, DE), Shlomo Ben Haim (London-GB) 1. Role of multimodal imaging in arrhythmia patients Reza Wakili (Munich, DE) 2. Risk stratification by autonomic biosignaling Axel Bauer (Munich, DE) 3. Role of sympathetic innervation in ARVD patients Matthias Paul (Munich, DE) 4. Autonomic testing for risk stratification in Long-QT patients Peter Schwartz (Milan, IT) 5. Renal Denervation—A treatment option for ventricular storm tachycardias Noel Boyle (Los Angeles, USA) MONDAY APRIL 20, 2015 4:00 PM–5:30 PM ROOM GAUGUIN Chaired Poster session D (Cont.) MONDAY APRIL 20, 2015 5:30 PM–6:15 PM ROOM COROT Debate 1 Successful RF ablation alone is an acceptable treatment for monomorphic, well-tolerated VT with an ejection fraction above 30 % Chairpersons: Francis Marchlinski, (Philadelphia, USA), Gerhard Steinbeck (Munich, DE) Protagonist: Philippe Maury (Toulouse, FR) Antagonist: Brian Olshansky (Iowa City, USA) MONDAY APRIL 20, 2015 5:30 PM–6:15 PM ROOM DIDEROT Debate 2

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Chairpersons: Berndt Lüderitz (Munich, DE), Pro Obel (Johannesburg, ZA) Rhythm control in patients with atrial fibrillation should not be pursued vigorously in the post AFFIRM era? Protagonist: A. John Camm (London, GB) Antagonist: Sanjeev Saksena (Warren, USA) MONDAY APRIL 20, 2015 5:30 PM–6:15 PM ROOM PASCAL Debate 3: Right ventricular apical pacing should be abandoned Chairpersons: Luigi Padeletti (Florence, IT), Pascal Defaye (Grenoble, FR) Protagonist: Carsten Israel (Bielefeld, DE) Antagonist: Eli Ovsyshcher (Beer Sheba, IL) TUESDAY APRIL 21, 2015 08:30 AM–10:00 AM ROOM DIDEROT Abstract session 9 ROOM DESCARTES Abstract session 10 ROOM PASCAL Abstract session 11 ROOM TBA Abstract session 12 Coffee Break TUESDAY APRIL 21, 2015 10:30 AM–12:00 PM ROOM DIDEROT Session SP-11 Unresolved questions in the management of cardiac arrhythmias Chairpersons: Edward Rowland (London, GB), Maurice Khoury (Beirut, LB) 1. How to interpret short runs of AF on Holter monitoring? Taya V. Glotzer (Hackensack, NJ, USA)

J Interv Card Electrophysiol (2015) 42:173–326

2. How much redo after a first AF ablation procedure? David Keane (Dublin, IE) 3. Does revascularization prevent SCD? Gerard Guiraudon (London, CA) 4. How safe are PVC’s in patients without structural heart disease? Charles Jazra (Beirut, LB) 5. Ablation of PVCs: When and how? Oussama Wazni (Cleveland, USA) TUESDAY APRIL 21, 2015 10:30 AM–12:00 AM ROOM DESCARTES SP-12 New tools and techniques for AF therapy Young German electrophysiologists—Session of the German EP Fellow program Chairpersons: Reza Wakili (Munich, DE), Roland Tilz (Hamburg DE) 1. Potential role of multimodal mapping for a better understanding of the AF substrate Armin Luik (Karlsruhe, DE) 2. Role of continuous ECG monitoring by implantable loop recorders Joern Schmitt (Giessen DE) 3. The nMARQ-catheter: initial experience and results Stephanie Fichtner (Munich DE) 4. Rotor mapping: do different tools lead to different results? Roland Tilz (Hamburg, DE) TUESDAY APRIL 21, 2015 10:30 AM–12:00 AM ROOM PASCAL WS-04 Current Issues in AF management Chairpersons: Roberto de Ponti (Varese, IT), Michiel Janse (Amsterdam, NL) 1. Remodelling and Anti-arrhythmic Agents Dobromir Dobrev (Essen, DE) 2. Monitoring Ablation Outcomes—what really happens to AF? Neil Sulke (Eastbourne, GB)

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3. Thoracoscopic Surgery and Hybrid Therapy Outcomes Alaadin Yilmaz (Amsterdam, NL) 4. Hot versus Cold—The latest outcomes of CRYO and RF techniques in paroxysmal and persistent AF Ross Hunter (London, GB) TUESDAY APRIL 21, 2015 10:30 AM–12:00 AM ROOM TOCQUEVILLE WS-05 Nightmares in catheter ablation: case presentations Chairpersons: Riccardo Cappato (Milan), Ali Oto (Ankara, TR) My worst case of… 1. Atrial flutter ablation Isabel Deisenhofer (Munich, DE) 2. Atrial fibrillation ablation Nicolas Lellouche (Paris, FR) 3. Accessory pathway ablation Peter Loh (Utrecht, NL) 4. Ventricular tachycardia ablation Bharat Kantharia (Houston, USA)

J Interv Card Electrophysiol (2015) 42:173–326

Abstract oral session 1: Atrial fibrillation ablation Sunday, April 19, 2015, 10:30 AM–12:00 PM 1–1 Abstract 18–21 EFFECT OF ANTIARRHYTHMICS DRUG INIT IATION ON READMISSION AFTER CATHETER ABLATION FOR ATRIAL FIBRILLATION Peter Noseworthy 1 , Holly Van Houten 1 , Lindsey Sangaralingham1, Abhishek Deshmuk1, Suraj Kapa1, Siva Mulpuru1, Christopher McLeod1, Samuel Asirvatham1, Nilay Shah1, Douglas Packer1 1 Mayo Clinic, Rochester, MN, United States Background: Hospital readmission, a commonly tracked indicator of quality and efficiency of care delivery, occurs in about 15 % patients within 90 days of undergoing catheter ablation for atrial fibrillation (AF). We sought to evaluate the impact on antiarrhythmic drug (AAD) initiation on the risk of readmission. Methods and Results: Using a large national administrative claims database, we identified all atrial fibrillation patients (age ≥ 18 years) who underwent catheter ablation between 2005 and 2013. We identified the subset of patients who had

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not been on an AAD in the 90 days prior to the ablation (n= 2542) and, among those, the patients in whom an AAD was initiated within 7 days of the ablation (n=826). A total of 387 (15.2 %) patients were readmitted within 90 days of ablation for any cause, and 161 (6.3 %) were readmitted with atrial fibrillation or atrial flutter as the primary discharge diagnosis. The readmission rate was significantly lower among patients who were initiated on an antiarrhythmic drug compared to those who were not (11.7 vs. 16.9 %, p=0.0007). In a multivariate model, age 65+years, Charlson index of ≥ 3, CHADS2 score of ≥ 3, and year of service in 2009–2010 were significantly associated with risk of readmission (p

Abstracts of the 11th Annual Congress of the European Cardiac Arrhythmia Society, April 19-21, 2015, Paris, France.

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