Original Article A Randomized Controlled Trial of Catheter Ablation Versus Medical Treatment of Atrial Fibrillation in Heart Failure (The CAMTAF Trial) Ross J. Hunter, MRCP, PhD; Thomas J. Berriman, MBBS; Ihab Diab, MD, MRCP; Ravindu Kamdar, MD, MRCP; Laura Richmond, MSc; Victoria Baker, MSc; Farai Goromonzi, MSc; Vinit Sawhney, MRCP; Edward Duncan, MRCP, PhD; Stephen P. Page, MD, MRCP; Waqas Ullah, MRCP; Beth Unsworth, PhD; Jamil Mayet, MD, FESC; Mehul Dhinoja, FRCP; Mark J. Earley, MD, FRCP; Simon Sporton, MD, FRCP; Richard J. Schilling, MD, FRCP
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Background—Restoring sinus rhythm in patients with heart failure (HF) and atrial fibrillation (AF) may improve left ventricular (LV) function and HF symptoms. We sought to compare the effect of a catheter ablation strategy with that of a medical rate control strategy in patients with persistent AF and HF. Methods and Results—Patients with persistent AF, symptomatic HF, and LV ejection fraction