RESEARCH ARTICLE
A Comparison of Radiologic Tumor Volume and Pathologic Tumor Volume in Renal Cell Carcinoma (RCC) See Min Choi1, Don Kyoung Choi2, Tae Heon Kim2, Byong Chang Jeong2, Seong Il Seo2, Seong Soo Jeon2, Hyun Moo Lee2, Han-Yong Choi2, Hwang Gyun Jeon3* 1 Department of Urology, Gyeongsang National University Hospital, Gyeongsang National University School of medicine, Jinju, Korea, 2 Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, 3 Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea * [email protected]
Abstract
OPEN ACCESS Citation: Choi SM, Choi DK, Kim TH, Jeong BC, Seo SI, Jeon SS, et al. (2015) A Comparison of Radiologic Tumor Volume and Pathologic Tumor Volume in Renal Cell Carcinoma (RCC). PLoS ONE 10(3): e0122019. doi:10.1371/journal.pone.0122019 Academic Editor: Surinder K. Batra, University of Nebraska Medical Center, UNITED STATES Received: November 30, 2014 Accepted: February 9, 2015 Published: March 23, 2015 Copyright: © 2015 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability Statement: All relevant data are within the paper. Funding: This study was supported by Samsung Biomedical Research Institute grant [#SMR113101]. HGJ received the funding. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have declared that no competing interests exist.
Objective To investigate the difference between preoperative radiologic tumor volume (RTV) and postoperative pathologic tumor volume (PTV) in patients who received nephrectomy for renal cell carcinoma (RCC).
Materials and Methods We reviewed 482 patients who underwent preoperative computed tomography (CT) within 4 weeks before radical or partial nephrectomy for renal cell carcinoma. RTV measured by a three dimensional rendering program was compared with PTV (π/6ⅹheightⅹlengthⅹwidth) measured in surgical specimen according to pathologic tumor size and histologic subtype. Correlation of the inter-quartile range (IQR) of the RTV and Fuhrman nuclear grade was also investigated.
Results There was a significant positive linear correlation between RTV and PTV (p
A Comparison of Radiologic Tumor Volume and Pathologic Tumor Volume in Renal Cell Carcinoma (RCC) See Min Choi1, Don Kyoung Choi2, Tae Heon Kim2, Byong Chang Jeong2, Seong Il Seo2, Seong Soo Jeon2, Hyun Moo Lee2, Han-Yong Choi2, Hwang Gyun Jeon3* 1 Department of Urology, Gyeongsang National University Hospital, Gyeongsang National University School of medicine, Jinju, Korea, 2 Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, 3 Department of Urology, Samsung Medical Center, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Seoul, Korea * [email protected]
Abstract
OPEN ACCESS Citation: Choi SM, Choi DK, Kim TH, Jeong BC, Seo SI, Jeon SS, et al. (2015) A Comparison of Radiologic Tumor Volume and Pathologic Tumor Volume in Renal Cell Carcinoma (RCC). PLoS ONE 10(3): e0122019. doi:10.1371/journal.pone.0122019 Academic Editor: Surinder K. Batra, University of Nebraska Medical Center, UNITED STATES Received: November 30, 2014 Accepted: February 9, 2015 Published: March 23, 2015 Copyright: © 2015 Choi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Data Availability Statement: All relevant data are within the paper. Funding: This study was supported by Samsung Biomedical Research Institute grant [#SMR113101]. HGJ received the funding. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have declared that no competing interests exist.
Objective To investigate the difference between preoperative radiologic tumor volume (RTV) and postoperative pathologic tumor volume (PTV) in patients who received nephrectomy for renal cell carcinoma (RCC).
Materials and Methods We reviewed 482 patients who underwent preoperative computed tomography (CT) within 4 weeks before radical or partial nephrectomy for renal cell carcinoma. RTV measured by a three dimensional rendering program was compared with PTV (π/6ⅹheightⅹlengthⅹwidth) measured in surgical specimen according to pathologic tumor size and histologic subtype. Correlation of the inter-quartile range (IQR) of the RTV and Fuhrman nuclear grade was also investigated.
Results There was a significant positive linear correlation between RTV and PTV (p
