www.nature.com/scientificreports
OPEN
received: 14 October 2015 accepted: 03 February 2016 Published: 22 February 2016
A combination of serum iron, ferritin and transferrin predicts outcome in patients with intracerebral hemorrhage Guang Yang1,3,*, Rong Hu1,*, Chao Zhang1,*, Christopher Qian2, Qian-Qian Luo3, Wing-Ho Yung2, Ya Ke2, Hua Feng1 & Zhong-Ming Qian1,3 Association of a high-serum ferritin with poor outcome showed that iron might play a detrimental role in the brain after intracerebral hemorrhage (ICH). Here, we investigated changes in serum iron, ferritin, transferrin (Tf) and ceruloplasmin (CP) in patients with ICH (n = 100) at day 1 (admission), 3, 7, 14 and 21 and those in control subjects (n = 75). The hematoma and edema volumes were also determined in ICH-patients on admission and at day 3. The Modified Rankin Scale (mRS) of 59 patients was ≥3 (poor outcome) and 41
OPEN
received: 14 October 2015 accepted: 03 February 2016 Published: 22 February 2016
A combination of serum iron, ferritin and transferrin predicts outcome in patients with intracerebral hemorrhage Guang Yang1,3,*, Rong Hu1,*, Chao Zhang1,*, Christopher Qian2, Qian-Qian Luo3, Wing-Ho Yung2, Ya Ke2, Hua Feng1 & Zhong-Ming Qian1,3 Association of a high-serum ferritin with poor outcome showed that iron might play a detrimental role in the brain after intracerebral hemorrhage (ICH). Here, we investigated changes in serum iron, ferritin, transferrin (Tf) and ceruloplasmin (CP) in patients with ICH (n = 100) at day 1 (admission), 3, 7, 14 and 21 and those in control subjects (n = 75). The hematoma and edema volumes were also determined in ICH-patients on admission and at day 3. The Modified Rankin Scale (mRS) of 59 patients was ≥3 (poor outcome) and 41
